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RELA RELA proto-oncogene, NF-kB subunit [ Gallus gallus (chicken) ]

Gene ID: 396027, updated on 5-Sep-2025
Symbol
RELAprovided by CGNC
Full Name
RELA proto-oncogene, NF-kB subunitprovided by CGNC
Primary source
CGNC:49615
See related
Ensembl:ENSGALG00010001277
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
RELB; GC-rich
Orthologs
human mouse all
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See RELA in Genome Data Viewer
Location:
chromosome: 39
Exon count:
11
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 39 Unlocalized Scaffold NW_024095974.1 (13724..21836, complement)

NW_024095974.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107050177 Neighboring gene ubiquinol-cytochrome c reductase complex assembly factor 3 Neighboring gene lysine acetyltransferase 5 Neighboring gene transmembrane protein 223 Neighboring gene nuclear RNA export factor 1

Genomic Sequence:
NW_024095974 Chromosome 39 Unlocalized Scaffold Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Up-regulation of the MyD88-dependent pathway of TLR signaling in spleen and caecum of young chickens infected with Salmonella serovar Pullorum. Li P, et al. Vet Microbiol, 2010 Jul 14. PMID 20053507
  2. The chicken RelB transcription factor has transactivation sequences and a tissue-specific expression pattern that are distinct from mammalian RelB. Piffat KA, et al. Mol Cell Biol Res Commun, 2001 Sep. PMID 11529676
  3. Isolation of the chicken NF-kappa B p65 subunit-encoding cDNA and characterization of its products. Ikeda T, et al. Gene, 1993 Nov 15. PMID 7916720
  4. Development of a chicken 5 K microarray targeted towards immune function. Smith J, et al. BMC Genomics, 2006 Mar 13. PMID 16533398, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to cytokine IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
transcription factor p65
Names
NF-kB p65 subunit
RELB proto-oncogene, NF-kB subunit
nuclear factor NF-kappa-B p65 subunit
transcription factor RelB homolog
v-rel avian reticuloendotheliosis viral oncogene homolog A
v-rel avian reticuloendotheliosis viral oncogene homolog B
v-rel reticuloendotheliosis viral oncogene homolog A
NP_001382967.1

Length

  • 559

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001396038.1 → NP_001382967.1  transcription factor p65

    Status: VALIDATED

    Source sequence(s)
    AM066754, D13721
    UniProtKB/Swiss-Prot
    P98152
    Related
    ENSGALP00010001500.1, ENSGALT00010002954.1
    Conserved Domains (2) summary
    cd07885
    Location:26 → 193
    RHD-n_RelA; N-terminal sub-domain of the Rel homology domain (RHD) of RelA
    cd01177
    Location:200 → 296
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NW_024095974.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    13724..21836 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_204850.1: Suppressed sequence

    Description
    NM_204850.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.

  2. NM_205129.1: Suppressed sequence

    Description
    NM_205129.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P51509.2 GenPept UniProtKB/Swiss-Prot:P51509
P98152.1 GenPept UniProtKB/Swiss-Prot:P98152

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials