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DNMT1 DNA methyltransferase 1 [ Gallus gallus (chicken) ]

Gene ID: 396011, updated on 14-Feb-2019

Summary

Symbol
DNMT1provided by CGNC
Full Name
DNA methyltransferase 1provided by CGNC
Primary source
CGNC:20270
See related
Ensembl:ENSGALG00000038018
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs

Genomic context

See DNMT1 in Genome Data Viewer
Location:
chromosome: 30
Exon count:
34
Annotation release Status Assembly Chr Location
104 current GRCg6a (GCF_000002315.5) 30 NC_028739.2 (988921..1011458)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) Unplaced Scaffold NT_464238.1 (7325..30408)
102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) Unplaced Scaffold NW_003769385.1 (237..12479, complement)
102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) Unplaced Scaffold NW_003771706.1 (4104..4491, complement)

Chromosome 30 - NC_028739.2Genomic Context describing neighboring genes Neighboring gene procollagen C-endopeptidase enhancer Neighboring gene sphingosine-1-phosphate receptor 2 Neighboring gene eukaryotic translation initiation factor 3, subunit G Neighboring gene suppressor of SWI4 1 homolog Neighboring gene uncharacterized LOC112531000

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA (cytosine-5-)-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
promoter-specific chromatin binding ISS
Inferred from Sequence or Structural Similarity
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
C-5 methylation of cytosine IEA
Inferred from Electronic Annotation
more info
 
DNA methylation on cytosine within a CG sequence IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Ras protein signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
 
maintenance of DNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of methylation-dependent chromatin silencing ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
DNA (cytosine-5)-methyltransferase 1
Names
DNA (cytosine-5-)-methyltransferase 1
DNA MTase GgaI
DNA MeTase
DNA methyltransferase GgaI
MCMT
m.GgaI
NP_996835.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_206952.1NP_996835.1  DNA (cytosine-5)-methyltransferase 1

    See identical proteins and their annotated locations for NP_996835.1

    Status: PROVISIONAL

    Source sequence(s)
    D43920
    UniProtKB/Swiss-Prot
    Q92072
    Related
    ENSGALP00000056402.2, ENSGALT00000051245.2
    Conserved Domains (6) summary
    COG0270
    Location:10531509
    Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
    cd04711
    Location:8761012
    BAH_Dnmt1_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
    cd04760
    Location:666788
    BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG ...
    pfam02008
    Location:557603
    zf-CXXC; CXXC zinc finger domain
    pfam06464
    Location:30100
    DMAP_binding; DMAP1-binding Domain
    pfam12047
    Location:310445
    DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCg6a Primary Assembly

Genomic

  1. NC_028739.2 Reference GRCg6a Primary Assembly

    Range
    988921..1011458
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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