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CACNA1S calcium voltage-gated channel subunit alpha1 S [ Gallus gallus (chicken) ]

Gene ID: 395985, updated on 13-Apr-2026
Symbol
CACNA1Sprovided by CGNC
Full Name
calcium voltage-gated channel subunit alpha1 Sprovided by CGNC
Primary source
CGNC:49591
See related
Ensembl:ENSGALG00010027086
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
CATSPER2
Orthologs
all
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Try the new Transcripts and proteins table
See CACNA1S in Genome Data Viewer
Location:
chromosome: 26
Exon count:
44
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 26 NC_052557.1 (295608..325281)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 26 NC_052598.1 (264709..294363)

Chromosome 26 - NC_052557.1Genomic Context describing neighboring genes Neighboring gene TBC1 domain family member 22B Neighboring gene uncharacterized LOC101747295 Neighboring gene Pim-1 proto-oncogene, serine/threonine kinase Neighboring gene kinesin family member 21B Neighboring gene E74 like ETS transcription factor 3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables high voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion import across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of voltage-gated calcium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
voltage-dependent L-type calcium channel subunit alpha-1S
Names
L-type calcium channel, alpha 1 subunit
calcium channel voltage-dependent L type alpha 1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
cation channel sperm associated 2
voltage-gated calcium channel subunit alpha Cav1.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001397698.1 → NP_001384627.1  voltage-dependent L-type calcium channel subunit alpha-1S isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) lacks the 29th exon.
    Source sequence(s)
    JAENSK010000356
    UniProtKB/TrEMBL
    A0A1D5PV02, A0A8V1AEH7

  2. NM_001397699.1 → NP_001384628.1  voltage-dependent L-type calcium channel subunit alpha-1S isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has the 29th exon.
    Source sequence(s)
    JAENSK010000356
    UniProtKB/TrEMBL
    A0A1D5PV02
    Related
    ENSGALP00010039916.1, ENSGALT00010065650.1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052557.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    295608..325281
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046904103.1 → XP_046760059.1  voltage-dependent L-type calcium channel subunit alpha-1S isoform X2

    UniProtKB/TrEMBL
    A0A1D5PV02

  2. XM_046904104.1 → XP_046760060.1  voltage-dependent L-type calcium channel subunit alpha-1S isoform X3

    UniProtKB/TrEMBL
    A0A1D5PV02, A0A8V1AEH7
    Related
    ENSGALP00010039914.1, ENSGALT00010065648.1

  3. XM_015298692.4 → XP_015154178.3  voltage-dependent L-type calcium channel subunit alpha-1S isoform X1

    UniProtKB/TrEMBL
    A0A1D5PV02
    Conserved Domains (1) summary
    smart01062
    Location:1517 → 1543
    Ca_chan_IQ; Voltage gated calcium channel IQ domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052598.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    264709..294363
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046932885.1 → XP_046788841.1  voltage-dependent L-type calcium channel subunit alpha-1S isoform X1

    UniProtKB/TrEMBL
    A0A1D5PV02

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001305147.1: Suppressed sequence

    Description
    NM_001305147.1: This RefSeq was removed because currently there is support for the protein but not for the transcript.

  2. NM_001305148.1: Suppressed sequence

    Description
    NM_001305148.1: This RefSeq was removed because currently there is support for the protein but not for the transcript.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O42398.1 GenPept UniProtKB/Swiss-Prot:O42398

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials