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RORB RAR related orphan receptor B [ Gallus gallus (chicken) ]

Gene ID: 395980, updated on 14-Feb-2019

Summary

Symbol
RORBprovided by CGNC
Full Name
RAR related orphan receptor Bprovided by CGNC
Primary source
CGNC:49589
See related
Ensembl:ENSGALG00000015150
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Summary
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]
Orthologs

Genomic context

See RORB in Genome Data Viewer
Location:
chromosome: Z
Exon count:
10
Annotation release Status Assembly Chr Location
104 current GRCg6a (GCF_000002315.5) Z NC_006127.5 (36554623..36687861)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) Z NC_006127.4 (36543163..36676401)
102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) Z NC_006127.3 (36402033..36535271)

Chromosome Z - NC_006127.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112530673 Neighboring gene annexin A1 Neighboring gene uncharacterized LOC112530580 Neighboring gene transient receptor potential cation channel subfamily M member 6

Genomic regions, transcripts, and products

General gene information

Markers

Homology

General protein information

Preferred Names
nuclear receptor ROR-beta
Names
nuclear orphan receptor ROR-beta

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205093.1NP_990424.1  nuclear receptor ROR-beta

    See identical proteins and their annotated locations for NP_990424.1

    Status: PROVISIONAL

    Source sequence(s)
    Y08638
    UniProtKB/TrEMBL
    Q98934
    Related
    ENSGALP00000024399.3, ENSGALT00000024445.6
    Conserved Domains (2) summary
    cd06939
    Location:210450
    NR_LBD_ROR_like; The ligand binding domain of Retinoid-related orphan receptors, of the nuclear receptor superfamily
    cd06968
    Location:397
    NR_DBD_ROR; DNA-binding domain of Retinoid-related orphan receptors (RORs) is composed of two C4-type zinc fingers

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCg6a Primary Assembly

Genomic

  1. NC_006127.5 Reference GRCg6a Primary Assembly

    Range
    36554623..36687861
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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