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FSHR follicle stimulating hormone receptor [ Gallus gallus (chicken) ]

Gene ID: 395962, updated on 5-Sep-2025
Symbol
FSHRprovided by CGNC
Full Name
follicle stimulating hormone receptorprovided by CGNC
Primary source
CGNC:6926
See related
Ensembl:ENSGALG00010019997
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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See FSHR in Genome Data Viewer
Location:
chromosome: 3
Exon count:
15
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (7507706..7718306)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (7550755..7663428)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110205 Neighboring gene uncharacterized LOC107052022 Neighboring gene uncharacterized LOC121110171 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC107052021 Neighboring gene luteinizing hormone/choriogonadotropin receptor Neighboring gene general transcription factor IIA, 1-like

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Identification of chicken FSHR gene promoter and the correlations between polymorphisms and egg production in Chinese native hens. Li X, et al. Reprod Domest Anim, 2019 Apr. PMID 30702781, Free PMC Article
  2. FSH stimulates lipid biosynthesis in chicken adipose tissue by upregulating the expression of its receptor FSHR. Cui H, et al. J Lipid Res, 2012 May. PMID 22345708, Free PMC Article
  3. The cDNA cloning and transient expression of a chicken gene encoding a follicle-stimulating hormone receptor. Wakabayashi N, et al. Gene, 1997 Sep 15. PMID 9332357
  4. Characterization of the chicken follicle-stimulating hormone receptor (cFSH-R) complementary deoxyribonucleic acid, and expression of cFSH-R messenger ribonucleic acid in the ovary. You S, et al. Biol Reprod, 1996 Nov. PMID 8902217
  5. Cooperative Effects of FOXL2 with the Members of TGF-β Superfamily on FSH Receptor mRNA Expression and Granulosa Cell Proliferation from Hen Prehierarchical Follicles. Qin N, et al. PLoS One, 2015. PMID 26496659, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. DNA sequencing was used to identify SNPs in the FSHR promoter sequence in both Dongxiang and Suken chickens.
    Title: Identification of chicken FSHR gene promoter and the correlations between polymorphisms and egg production in Chinese native hens.
  2. Cooperative effects have been found of FOXL2 with the members of TGF-beta superfamily on FSH receptor mRNA expression and granulosa cell proliferation from hen prehierarchical follicles.
    Title: Cooperative Effects of FOXL2 with the Members of TGF-β Superfamily on FSH Receptor mRNA Expression and Granulosa Cell Proliferation from Hen Prehierarchical Follicles.
  3. Bone morphogenetic protein 6 promotes FSH receptor and anti-Mullerian hormone mRNA expression in granulosa cells.
    Title: Bone morphogenetic protein 6 promotes FSH receptor and anti-Müllerian hormone mRNA expression in granulosa cells from hen prehierarchal follicles.
  4. FSH stimulates lipid biosynthesis by upregulating Fshr mRNA expression in abdominal adipose tissue of chickens
    Title: FSH stimulates lipid biosynthesis in chicken adipose tissue by upregulating the expression of its receptor FSHR.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables follicle-stimulating hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in follicle-stimulating hormone signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in male gonad development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
follicle-stimulating hormone receptor
Names
FSH-R
follitropin receptor

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205079.2 → NP_990410.2  follicle-stimulating hormone receptor precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000061
    UniProtKB/Swiss-Prot
    P79763, Q90719
    Related
    ENSGALP00010028476.1, ENSGALT00010048295.1
    Conserved Domains (3) summary
    sd00033
    Location:72 → 96
    LRR_RI; leucine-rich repeat [structural motif]
    cd14964
    Location:365 → 389
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:363 → 637
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    7507706..7718306
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025148544.2 → XP_025004312.1  follicle-stimulating hormone receptor isoform X2

    UniProtKB/TrEMBL
    A0A3Q2ULE6, A0A3Q3A7G8
    Related
    ENSGALP00010028478.1, ENSGALT00010048299.1
    Conserved Domains (5) summary
    sd00033
    Location:26 → 50
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12369
    Location:236 → 303
    GnHR_trans; Gonadotropin hormone receptor transmembrane region
    cd15360
    Location:319 → 343
    7tmA_FSH-R; TM helix 1 [structural motif]
    cl26222
    Location:15 → 170
    LRR_5; Leucine rich repeats (6 copies)
    cl28897
    Location:317 → 591
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_040696843.2 → XP_040552777.1  follicle-stimulating hormone receptor isoform X3

    UniProtKB/TrEMBL
    A0A3Q2ULE6
    Conserved Domains (3) summary
    sd00033
    Location:15 → 39
    LRR_RI; leucine-rich repeat [structural motif]
    cd14964
    Location:307 → 333
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:306 → 580
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  3. XM_040696841.2 → XP_040552775.1  follicle-stimulating hormone receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZC65
    Conserved Domains (2) summary
    sd00033
    Location:83 → 107
    LRR_RI; leucine-rich repeat [structural motif]
    cd15360
    Location:373 → 647
    7tmA_FSH-R; follicle-stimulating hormone receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  4. XM_040696844.2 → XP_040552778.1  follicle-stimulating hormone receptor isoform X4

    UniProtKB/TrEMBL
    B8Y927
    Conserved Domains (1) summary
    sd00033
    Location:83 → 107
    LRR_RI; leucine-rich repeat [structural motif]

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    7550755..7663428
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046913179.1 → XP_046769135.1  follicle-stimulating hormone receptor isoform X2

    UniProtKB/TrEMBL
    A0A3Q2ULE6

  2. XM_046913181.1 → XP_046769137.1  follicle-stimulating hormone receptor isoform X3

    UniProtKB/TrEMBL
    A0A3Q2ULE6

  3. XM_046913178.1 → XP_046769134.1  follicle-stimulating hormone receptor isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZC65

  4. XM_046913182.1 → XP_046769138.1  follicle-stimulating hormone receptor isoform X4

    UniProtKB/TrEMBL
    B8Y927

  5. XM_046913180.1 → XP_046769136.1  follicle-stimulating hormone receptor isoform X5

    UniProtKB/TrEMBL
    A0A3Q2ULE6
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P79763.1 GenPept UniProtKB/Swiss-Prot:P79763

Gene LinkOut

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