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CNP 2',3'-cyclic nucleotide 3' phosphodiesterase [ Gallus gallus (chicken) ]

Gene ID: 395921, updated on 16-Jun-2026
Official Symbol
CNPprovided by CGNC
Official Full Name
2',3'-cyclic nucleotide 3' phosphodiesteraseprovided by CGNC
Primary source
CGNC:49552
See related
Ensembl:ENSGALG00010023043
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
Try the new Gene page
Try the new Transcripts and proteins table
See CNP in Genome Data Viewer
Location:
chromosome: 27
Exon count:
4
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 27 NC_052558.1 (4732335..4737499)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 27 NC_052599.1 (5894561..5899744)

Chromosome 27 - NC_052558.1Genomic Context describing neighboring genes Neighboring gene kelch like family member 11 Neighboring gene ATP citrate lyase Neighboring gene tetratricopeptide repeat domain 25 Neighboring gene DnaJ heat shock protein family (Hsp40) member C7 Neighboring gene NFKB inhibitor interacting Ras like 2 Neighboring gene zinc finger protein 385C Neighboring gene C17orf113 homolog

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cyclic nucleotide catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
2',3'-cyclic-nucleotide 3'-phosphodiesterase
Names
CNP2
NP_990381.1
XP_024999723.2
XP_046789257.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205050.2NP_990381.1  2',3'-cyclic-nucleotide 3'-phosphodiesterase

    See identical proteins and their annotated locations for NP_990381.1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000365
    UniProtKB/TrEMBL
    A0A8V0ZYF9, F1NPX6, O57389
    Related
    ENSGALP00010033935.1, ENSGALT00010056102.1
    Conserved Domains (3) summary
    smart00382
    Location:54146
    AAA; ATPases associated with a variety of cellular activities
    pfam05881
    Location:186397
    CNPase; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
    cl17190
    Location:49148
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052558.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    4732335..4737499
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025143955.3XP_024999723.2  2',3'-cyclic-nucleotide 3'-phosphodiesterase isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZSX0
    Related
    ENSGALP00010033933.1, ENSGALT00010056097.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052599.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    5894561..5899744
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046933301.1XP_046789257.1  2',3'-cyclic-nucleotide 3'-phosphodiesterase isoform X1