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EYA2 EYA transcriptional coactivator and phosphatase 2 [ Gallus gallus (chicken) ]

Gene ID: 395745, updated on 20-Jun-2026
Symbol
EYA2provided by CGNC
Full Name
EYA transcriptional coactivator and phosphatase 2provided by CGNC
Primary source
CGNC:49455
See related
Ensembl:ENSGALG00010023863
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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See EYA2 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
21
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 20 NC_052551.1 (6011302..6104491)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 20 NC_052592.1 (5804684..5897543)

Chromosome 20 - NC_052551.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 13 member 3 Neighboring gene solute carrier family 2 member 10 Neighboring gene TP53 regulating kinase Neighboring gene uncharacterized LOC121107333 Neighboring gene uncharacterized LOC107054876 Neighboring gene zinc finger MYND-type containing 8 Neighboring gene nuclear receptor coactivator 3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Chicken Eyes absent 2 gene: isolation and expression pattern during development. Mishima N, et al. Int J Dev Biol, 1998 Nov. PMID 9879708
  2. Eya1 and Eya2 gene expression is down-regulated during somitic myogenesis in the cadmium-induced omphalocele chick model. Doi T, et al. J Pediatr Surg, 2012 Jun. PMID 22703781
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
protein phosphatase EYA2
Names
eyes absent homolog 2
eyes absent 2
NP_990246.2
XP_015152203.2
XP_024997931.1
XP_024997932.1
XP_024997933.1
XP_024997934.1
XP_024997935.2
XP_024997936.1
XP_024997937.1
XP_024997939.1
XP_024997940.1
XP_024997941.1
XP_024997943.1
XP_040506573.1
XP_040506574.1
XP_040506576.1
XP_046786531.1
XP_046786532.1
XP_046786533.1
XP_046786534.1
XP_046786535.1
XP_046786536.1
XP_046786537.1
XP_046786538.1
XP_046786539.1
XP_046786540.1
XP_046786541.1
XP_046786542.1
XP_046786543.1
XP_046786544.1
XP_046786545.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204915.2 → NP_990246.2  protein phosphatase EYA2

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000328
    UniProtKB/TrEMBL
    A0A8V0ZPG9
    Related
    ENSGALP00010035349.1, ENSGALT00010058194.1
    Conserved Domains (1) summary
    cd02601
    Location:263 → 534
    HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052551.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    6011302..6104491
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025142163.3 → XP_024997931.1  eyes absent homolog 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZPG9, A0A8V0ZYE4
    Conserved Domains (1) summary
    cd02601
    Location:278 → 549
    HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

  2. XM_025142165.3 → XP_024997933.1  eyes absent homolog 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZPG9
    Conserved Domains (1) summary
    cd02601
    Location:278 → 527
    HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

  3. XM_025142166.3 → XP_024997934.1  eyes absent homolog 2 isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZPG9
    Conserved Domains (1) summary
    cd02601
    Location:260 → 529
    HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

  4. XM_025142164.3 → XP_024997932.1  eyes absent homolog 2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZPG9
    Related
    ENSGALP00010035351.1, ENSGALT00010058196.1
    Conserved Domains (1) summary
    cd02601
    Location:263 → 534
    HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

  5. XM_025142168.3 → XP_024997936.1  eyes absent homolog 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZPG9, A0A8V0ZYE4
    Related
    ENSGALP00010035346.1, ENSGALT00010058190.1
    Conserved Domains (1) summary
    cd02601
    Location:278 → 549
    HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

  6. XM_025142172.3 → XP_024997940.1  eyes absent homolog 2 isoform X7

    UniProtKB/TrEMBL
    A0A8V1A290
    Conserved Domains (1) summary
    cd02601
    Location:239 → 510
    HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

  7. XM_040650639.2 → XP_040506573.1  eyes absent homolog 2 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZPG9
    Conserved Domains (1) summary
    cd02601
    Location:263 → 512
    HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

  8. XM_040650640.2 → XP_040506574.1  eyes absent homolog 2 isoform X6

    UniProtKB/TrEMBL
    A0A8V0ZPG9
    Conserved Domains (1) summary
    cd02601
    Location:245 → 514
    HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

  9. XM_025142167.3 → XP_024997935.2  eyes absent homolog 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZPG9, A0A8V0ZYE4

  10. XM_015296717.4 → XP_015152203.2  eyes absent homolog 2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZPG9
    Related
    ENSGALP00010035333.1, ENSGALT00010058175.1

  11. XM_025142169.3 → XP_024997937.1  eyes absent homolog 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZPG9, A0A8V0ZYE4
    Conserved Domains (1) summary
    cd02601
    Location:278 → 549
    HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

  12. XM_025142171.3 → XP_024997939.1  eyes absent homolog 2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZPG9
    Conserved Domains (1) summary
    cd02601
    Location:263 → 534
    HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

  13. XM_025142173.3 → XP_024997941.1  eyes absent homolog 2 isoform X8

    UniProtKB/TrEMBL
    A0A8V1A290
    Conserved Domains (1) summary
    cd02601
    Location:226 → 497
    HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

  14. XM_040650642.2 → XP_040506576.1  eyes absent homolog 2 isoform X9

    UniProtKB/TrEMBL
    A0A8V1A290
    Conserved Domains (1) summary
    cd02601
    Location:205 → 476
    HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

  15. XM_025142175.3 → XP_024997943.1  eyes absent homolog 2 isoform X10

    UniProtKB/TrEMBL
    A0A8V1A290
    Conserved Domains (1) summary
    cd02601
    Location:197 → 468
    HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052592.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    5804684..5897543
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046930575.1 → XP_046786531.1  eyes absent homolog 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZPG9

  2. XM_046930578.1 → XP_046786534.1  eyes absent homolog 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZPG9

  3. XM_046930579.1 → XP_046786535.1  eyes absent homolog 2 isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZPG9

  4. XM_046930577.1 → XP_046786533.1  eyes absent homolog 2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZPG9, Q9YI56

  5. XM_046930576.1 → XP_046786532.1  eyes absent homolog 2 isoform X11

    UniProtKB/TrEMBL
    A0A8V0ZPI4

  6. XM_046930580.1 → XP_046786536.1  eyes absent homolog 2 isoform X12

    UniProtKB/TrEMBL
    A0A8V0ZPI4

  7. XM_046930581.1 → XP_046786537.1  eyes absent homolog 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZPG9

  8. XM_046930586.1 → XP_046786542.1  eyes absent homolog 2 isoform X7

    UniProtKB/TrEMBL
    A0A8V1A290

  9. XM_046930584.1 → XP_046786540.1  eyes absent homolog 2 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZPG9

  10. XM_046930585.1 → XP_046786541.1  eyes absent homolog 2 isoform X6

    UniProtKB/TrEMBL
    A0A8V0ZPG9

  11. XM_046930582.1 → XP_046786538.1  eyes absent homolog 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZPG9

  12. XM_046930583.1 → XP_046786539.1  eyes absent homolog 2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZPG9, Q9YI56

  13. XM_046930587.1 → XP_046786543.1  eyes absent homolog 2 isoform X8

    UniProtKB/TrEMBL
    A0A8V1A290

  14. XM_046930588.1 → XP_046786544.1  eyes absent homolog 2 isoform X9

    UniProtKB/TrEMBL
    A0A8V1A290

  15. XM_046930589.1 → XP_046786545.1  eyes absent homolog 2 isoform X10

    UniProtKB/TrEMBL
    A0A8V1A290
Nucleotide Protein Strain
Heading Accession and Version

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