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FLT4 fms related tyrosine kinase 4 [ Gallus gallus (chicken) ]

Gene ID: 395742, updated on 3-Dec-2024
Symbol
FLT4provided by CGNC
Full Name
fms related tyrosine kinase 4provided by CGNC
Primary source
CGNC:49452
See related
Ensembl:ENSGALG00010016867
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
VEGFR3
Orthologs
human mouse all
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See FLT4 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
30
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 13 NC_052544.1 (12951742..12998047)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 13 NC_052585.1 (12965720..13012015)

Chromosome 13 - NC_052544.1Genomic Context describing neighboring genes Neighboring gene neuropeptide Y receptor Y7 Neighboring gene tripartite motif containing 105 Neighboring gene ring finger protein 130 Neighboring gene TBC1 domain family member 9B

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A novel VEGFR3 mutation causes Milroy disease. Butler MG, et al. Am J Med Genet A, 2007 Jun 1. PMID 17458866
  2. Early endocardial morphogenesis requires Scl/Tal1. Bussmann J, et al. PLoS Genet, 2007 Aug. PMID 17722983, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
vascular endothelial growth factor receptor 3
Names
tyrosine kinase VEGFR-3
NP_001280022.2
XP_015149228.2
XP_015149230.2
XP_040502788.1
XP_046782793.1
XP_046782794.1
XP_046782795.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001293093.2 → NP_001280022.2  vascular endothelial growth factor receptor 3 precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000256
    UniProtKB/TrEMBL
    A0A8V0YXZ9

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052544.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    12951742..12998047
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015293742.4 → XP_015149228.2  vascular endothelial growth factor receptor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YXZ9
    Related
    ENSGALP00010023668.1, ENSGALT00010040703.1
    Conserved Domains (6) summary
    smart00408
    Location:707 → 769
    IGc2; Immunoglobulin C-2 Type
    smart00409
    Location:250 → 337
    IG; Immunoglobulin
    smart00410
    Location:578 → 673
    IG_like; Immunoglobulin like
    cd05102
    Location:851 → 1189
    PTKc_VEGFR3; Catalytic domain of the Protein Tyrosine Kinase, Vascular Endothelial Growth Factor Receptor 3
    pfam17988
    Location:784 → 818
    VEGFR-2_TMD; VEGFR-2 Transmembrane domain
    cd00096
    Location:700 → 704
    Ig; Ig strand A' [structural motif]

  2. XM_040646854.2 → XP_040502788.1  vascular endothelial growth factor receptor 3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YXZ9
    Conserved Domains (6) summary
    smart00408
    Location:707 → 769
    IGc2; Immunoglobulin C-2 Type
    smart00409
    Location:250 → 337
    IG; Immunoglobulin
    smart00410
    Location:578 → 673
    IG_like; Immunoglobulin like
    cd05102
    Location:851 → 1189
    PTKc_VEGFR3; Catalytic domain of the Protein Tyrosine Kinase, Vascular Endothelial Growth Factor Receptor 3
    pfam17988
    Location:784 → 818
    VEGFR-2_TMD; VEGFR-2 Transmembrane domain
    cd00096
    Location:700 → 704
    Ig; Ig strand A' [structural motif]

  3. XM_015293744.4 → XP_015149230.2  vascular endothelial growth factor receptor 3 isoform X3

    UniProtKB/TrEMBL
    A0A8V0YXZ9
    Conserved Domains (5) summary
    smart00408
    Location:707 → 769
    IGc2; Immunoglobulin C-2 Type
    smart00409
    Location:250 → 337
    IG; Immunoglobulin
    smart00410
    Location:578 → 673
    IG_like; Immunoglobulin like
    cd05102
    Location:851 → 1189
    PTKc_VEGFR3; Catalytic domain of the Protein Tyrosine Kinase, Vascular Endothelial Growth Factor Receptor 3
    pfam17988
    Location:784 → 818
    VEGFR-2_TMD; VEGFR-2 Transmembrane domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052585.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    12965720..13012015
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046926837.1 → XP_046782793.1  vascular endothelial growth factor receptor 3 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YXZ9

  2. XM_046926838.1 → XP_046782794.1  vascular endothelial growth factor receptor 3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YXZ9

  3. XM_046926839.1 → XP_046782795.1  vascular endothelial growth factor receptor 3 isoform X3

    UniProtKB/TrEMBL
    A0A8V0YXZ9
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials