HOXB8 homeobox B8 [Gallus gallus (chicken)] - Gene

Summary

Symbol: HOXB8provided by CGNC
Full Name: homeobox B8provided by CGNC
Primary source: CGNC:66213
See related: Ensembl:ENSGALG00010021446
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: OX2.4; Hoxb-8; CHOX-2.4
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 27

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	27	NC_052558.1 (3402859..3404508)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	27	NC_052599.1 (4534773..4536422)

Chromosome 27 - NC_052558.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Copy number variation in HOXB7 and HOXB8 involves in the formation of beard trait in chickens.
Title: Copy number variation in HOXB7 and HOXB8 involves in the formation of beard trait in chickens.
The results strongly suggest the Mb allele leading to the Muffs and beard phenotype in chickens leads to an altered ectopic expression of a homeotic gene HOXB8, to suggest a novel role for HOXB8 in modulating the regional development of the feather.
Title: A Complex Structural Variation on Chromosome 27 Leads to the Ectopic Expression of HOXB8 and the Muffs and Beard Phenotype in Chickens.
Data suggest that HoxB8 acts by maintaining noradrenergic properties transiently expressed in ciliary neuron progenitors during normal development.
Title: HoxB8 in noradrenergic specification and differentiation of the autonomic nervous system.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: homeobox protein Hox-B8

Names: Homeobox protein Hox-2.4; homeo box B8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.