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HMGB1 high mobility group box 1 [ Gallus gallus (chicken) ]

Gene ID: 395724, updated on 5-Sep-2025
Official Symbol
HMGB1provided by CGNC
Official Full Name
high mobility group box 1provided by CGNC
Primary source
CGNC:49444
See related
Ensembl:ENSGALG00010007011
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
HMG1; HMG-1
Orthologs
human mouse all
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See HMGB1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (174950807..175004162)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (175033019..175086396)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene transfer RNA asparagine (anticodon GUU) Neighboring gene transfer RNA valine (anticodon AAC) Neighboring gene ubiquitin specific peptidase like 1 Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC107052100 Neighboring gene microRNA 1646 Neighboring gene katanin catalytic subunit A1 like 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Distinct domains in HMGB1 are involved in specific intramolecular and nucleosomal interactions. Kawase T, et al. Biochemistry, 2008 Dec 30. PMID 19102706
  2. Selection of a cDNA clone for chicken high-mobility-group 1 (HMG1) protein through its unusually conserved 3'-untranslated region, and improved expression of recombinant HMG1 in Escherichia coli. Lee KB, et al. Gene, 1998 Dec 28. PMID 9931456
  3. The chicken genome contains no HMG1 retropseudogenes but a functional HMG1 gene with long introns. Lum HK, et al. Biochim Biophys Acta, 2000 Sep 7. PMID 10978508
  4. The effect of the acidic tail on the DNA-binding properties of the HMG1,2 class of proteins: insights from tail switching and tail removal. Lee KB, et al. J Mol Biol, 2000 Nov 24. PMID 11080451
  5. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding, bending IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
high mobility group protein B1
Names
high mobility group 1 protein
high mobility group protein 1
high mobility group protein HMG1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204902.2 → NP_990233.1  high mobility group protein B1

    See identical proteins and their annotated locations for NP_990233.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ851648
    UniProtKB/Swiss-Prot
    H9BNX0, Q9PUK9, Q9YH06
    Conserved Domains (2) summary
    pfam00505
    Location:95 → 162
    HMG_box; HMG (high mobility group) box
    pfam09011
    Location:6 → 78
    HMG_box_2; HMG-box domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    174950807..175004162
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040653291.2 → XP_040509225.1  high mobility group protein B1 isoform X1

    UniProtKB/Swiss-Prot
    H9BNX0, Q9PUK9, Q9YH06
    Related
    ENSGALP00010009413.1, ENSGALT00010016656.1
    Conserved Domains (2) summary
    pfam00505
    Location:95 → 162
    HMG_box; HMG (high mobility group) box
    pfam09011
    Location:6 → 78
    HMG_box_2; HMG-box domain

  2. XM_040653347.2 → XP_040509281.1  high mobility group protein B1 isoform X1

    UniProtKB/Swiss-Prot
    H9BNX0, Q9PUK9, Q9YH06
    Conserved Domains (2) summary
    pfam00505
    Location:95 → 162
    HMG_box; HMG (high mobility group) box
    pfam09011
    Location:6 → 78
    HMG_box_2; HMG-box domain

  3. XM_015277670.3 → XP_015133156.1  high mobility group protein B1 isoform X1

    UniProtKB/Swiss-Prot
    H9BNX0, Q9PUK9, Q9YH06
    Conserved Domains (2) summary
    pfam00505
    Location:95 → 162
    HMG_box; HMG (high mobility group) box
    pfam09011
    Location:6 → 78
    HMG_box_2; HMG-box domain

  4. XM_046906974.1 → XP_046762930.1  high mobility group protein B1 isoform X2

  5. XM_046907210.1 → XP_046763166.1  high mobility group protein B1 isoform X1

    UniProtKB/Swiss-Prot
    H9BNX0, Q9PUK9, Q9YH06

  6. XM_015277667.4 → XP_015133153.1  high mobility group protein B1 isoform X1

    UniProtKB/Swiss-Prot
    H9BNX0, Q9PUK9, Q9YH06
    Related
    ENSGALP00010009408.1, ENSGALT00010016643.1
    Conserved Domains (2) summary
    pfam00505
    Location:95 → 162
    HMG_box; HMG (high mobility group) box
    pfam09011
    Location:6 → 78
    HMG_box_2; HMG-box domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    175033019..175086396
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046906696.1 → XP_046762652.1  high mobility group protein B1 isoform X1

    UniProtKB/Swiss-Prot
    H9BNX0, Q9PUK9, Q9YH06

  2. XM_046906699.1 → XP_046762655.1  high mobility group protein B1 isoform X1

    UniProtKB/Swiss-Prot
    H9BNX0, Q9PUK9, Q9YH06

  3. XM_046906698.1 → XP_046762654.1  high mobility group protein B1 isoform X1

    UniProtKB/Swiss-Prot
    H9BNX0, Q9PUK9, Q9YH06

  4. XM_046906697.1 → XP_046762653.1  high mobility group protein B1 isoform X2

  5. XM_046906701.1 → XP_046762657.1  high mobility group protein B1 isoform X1

    UniProtKB/Swiss-Prot
    H9BNX0, Q9PUK9, Q9YH06

  6. XM_046906700.1 → XP_046762656.1  high mobility group protein B1 isoform X1

    UniProtKB/Swiss-Prot
    H9BNX0, Q9PUK9, Q9YH06
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9YH06.1 GenPept UniProtKB/Swiss-Prot:Q9YH06

Gene LinkOut

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