IL6ST interleukin 6 signal transducer [Gallus gallus (chicken)] - Gene

Summary

Symbol: IL6STprovided by CGNC
Full Name: interleukin 6 signal transducerprovided by CGNC
Primary source: CGNC:10911
See related: Ensembl:ENSGALG00010012930
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: GP130
Orthologs: human mouse all
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Genomic context

Location:: chromosome: Z

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	Z	NC_052572.1 (17565706..17603673, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	Z	NC_059536.1 (17565706..17603673, complement)

Chromosome Z - NC_052572.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cytokine binding	IEA Inferred from Electronic Annotation more info	PubMed
enables cytokine receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cytokine-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed
part_of receptor complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: interleukin-6 receptor subunit beta

Names: glycoprotein 130; interleukin 6 signal transducer (gp130, oncostatin M receptor)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204871.2 → NP_990202.1 interleukin-6 receptor subunit beta precursor

See identical proteins and their annotated locations for NP_990202.1

Status: VALIDATED

Source sequence(s)

JAENSK010000089

UniProtKB/TrEMBL

A0A8V0YBA0, F1N940, Q9W6U9

Related

ENSGALP00010018050.1, ENSGALT00010031050.1

Conserved Domains (4) summary

smart00060
Location:523 → 603

FN3; Fibronectin type 3 domain

cd00063
Location:227 → 325

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam06328
Location:29 → 115

Lep_receptor_Ig; Ig-like C2-type domain

cl21522
Location:127 → 217

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

17565706..17603673 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040655417.2 → XP_040511351.1 interleukin-6 receptor subunit beta isoform X2

UniProtKB/TrEMBL

A0A8V0YBA0, F1N940, Q9W6U9

Conserved Domains (4) summary

smart00060
Location:523 → 603

FN3; Fibronectin type 3 domain

cd00063
Location:227 → 325

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam06328
Location:29 → 115

Lep_receptor_Ig; Ig-like C2-type domain

cl21522
Location:127 → 217

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_040655416.2 → XP_040511350.2 interleukin-6 receptor subunit beta isoform X1

Related

ENSGALP00010018047.1, ENSGALT00010031044.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

17565706..17603673 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046934788.1 → XP_046790744.1 interleukin-6 receptor subunit beta isoform X2

UniProtKB/TrEMBL

F1N940, Q9W6U9
XM_046934787.1 → XP_046790743.1 interleukin-6 receptor subunit beta isoform X1