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HBEGF heparin binding EGF like growth factor [ Gallus gallus (chicken) ]

Gene ID: 395654, updated on 17-Aug-2024
Symbol
HBEGFprovided by CGNC
Full Name
heparin binding EGF like growth factorprovided by CGNC
Primary source
CGNC:628
See related
Ensembl:ENSGALG00010008688
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
HEGFL; HB-EGF
Orthologs
human mouse all
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See HBEGF in Genome Data Viewer
Location:
chromosome: 13
Exon count:
6
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 13 NC_052544.1 (277318..283833)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 13 NC_052585.1 (485063..491577)

Chromosome 13 - NC_052544.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 4E binding protein 3 Neighboring gene ankyrin repeat and KH domain containing 1 Neighboring gene solute carrier family 4 member 9 Neighboring gene uncharacterized LOC107054478 Neighboring gene prefoldin subunit 1 Neighboring gene cysteine rich transmembrane module containing 1 Neighboring gene purine rich element binding protein A

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Heparin-binding epidermal growth factor-like growth factor, a v-Jun target gene, induces oncogenic transformation. Fu Sl, et al. Proc Natl Acad Sci U S A, 1999 May 11. PMID 10318950, Free PMC Article
  2. Cornichon-like protein facilitates secretion of HB-EGF and regulates proper development of cranial nerves. Hoshino H, et al. Mol Biol Cell, 2007 Apr. PMID 17229890, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CNIH2 gene facilitated the secretion of HB-EGF in the developing chick brain
    Title: Cornichon-like protein facilitates secretion of HB-EGF and regulates proper development of cranial nerves.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heparin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in epidermal growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of epidermal growth factor-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of mitotic nuclear division IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
proheparin-binding EGF-like growth factor

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204849.2 → NP_990180.1  proheparin-binding EGF-like growth factor precursor

    See identical proteins and their annotated locations for NP_990180.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000254
    UniProtKB/Swiss-Prot
    Q9W7C5
    Related
    ENSGALP00010011929.1, ENSGALT00010020605.1
    Conserved Domains (2) summary
    PHA02887
    Location:97 → 147
    PHA02887; EGF-like protein; Provisional
    PHA03099
    Location:119 → 188
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052544.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    277318..283833
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052585.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    485063..491577
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W7C5.1 GenPept UniProtKB/Swiss-Prot:Q9W7C5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.