Format

Send to:

Choose Destination

EPAS1 endothelial PAS domain protein 1 [ Gallus gallus (chicken) ]

Gene ID: 395596, updated on 14-Feb-2019

Summary

Symbol
EPAS1provided by CGNC
Full Name
endothelial PAS domain protein 1provided by CGNC
Primary source
CGNC:49393
See related
Ensembl:ENSGALG00000010005
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
HIF2a
Orthologs

Genomic context

See EPAS1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
17
Annotation release Status Assembly Chr Location
104 current GRCg6a (GCF_000002315.5) 3 NC_006090.5 (26671415..26748494)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 3 NC_006090.4 (26625940..26703017)
102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) 3 NC_006090.3 (25925105..25982708)

Chromosome 3 - NC_006090.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107052922 Neighboring gene protein kinase C epsilon Neighboring gene uncharacterized LOC107052923 Neighboring gene uncharacterized LOC101751252 Neighboring gene uncharacterized LOC107052973

Genomic regions, transcripts, and products

Bibliography

General gene information

Homology

General protein information

Preferred Names
endothelial PAS domain-containing protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204807.2NP_990138.1  endothelial PAS domain-containing protein 1

    See identical proteins and their annotated locations for NP_990138.1

    Status: PROVISIONAL

    Source sequence(s)
    AF129813
    UniProtKB/TrEMBL
    Q9W7C6
    Related
    ENSGALP00000058033.1, ENSGALT00000046856.3
    Conserved Domains (6) summary
    smart00091
    Location:86147
    PAS; PAS domain
    cd00083
    Location:1268
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:240339
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam08447
    Location:253340
    PAS_3; PAS fold
    pfam08778
    Location:830866
    HIF-1a_CTAD; HIF-1 alpha C terminal transactivation domain
    pfam11413
    Location:516548
    HIF-1; Hypoxia-inducible factor-1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCg6a Primary Assembly

Genomic

  1. NC_006090.5 Reference GRCg6a Primary Assembly

    Range
    26671415..26748494
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015283618.2XP_015139104.1  endothelial PAS domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A1D5PQ37
    Conserved Domains (6) summary
    smart00091
    Location:90151
    PAS; PAS domain
    cd00083
    Location:2072
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:244343
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam08447
    Location:257344
    PAS_3; PAS fold
    pfam08778
    Location:834870
    HIF-1a_CTAD; HIF-1 alpha C terminal transactivation domain
    pfam11413
    Location:520552
    HIF-1; Hypoxia-inducible factor-1
  2. XM_015283619.2XP_015139105.1  endothelial PAS domain-containing protein 1 isoform X2

    Conserved Domains (6) summary
    smart00091
    Location:90151
    PAS; PAS domain
    cd00083
    Location:2072
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:244343
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam08447
    Location:257344
    PAS_3; PAS fold
    pfam08778
    Location:830866
    HIF-1a_CTAD; HIF-1 alpha C terminal transactivation domain
    pfam11413
    Location:516548
    HIF-1; Hypoxia-inducible factor-1
Support Center