U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

BOK BCL2 family apoptosis regulator BOK [ Gallus gallus (chicken) ]

Gene ID: 395445, updated on 13-Apr-2026
Official Symbol
BOKprovided by CGNC
Official Full Name
BCL2 family apoptosis regulator BOKprovided by CGNC
Primary source
CGNC:4304
See related
Ensembl:ENSGALG00010023473
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See BOK in Genome Data Viewer
Location:
chromosome: 9
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 9 NC_052540.1 (4744672..4764408)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 9 NC_052581.1 (4577434..4597837)

Chromosome 9 - NC_052540.1Genomic Context describing neighboring genes Neighboring gene FERM, ARH/RhoGEF and pleckstrin domain protein 2 Neighboring gene uncharacterized LOC107051860 Neighboring gene serine/threonine kinase 25 Neighboring gene ETS variant 5 Neighboring gene diacylglycerol kinase gamma

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Evolutionarily conserved Bok proteins in the Bcl-2 family. Zhang H, et al. FEBS Lett, 2000 Sep 1. PMID 11034351
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extrinsic apoptotic signaling pathway in absence of ligand IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intrinsic apoptotic signaling pathway in response to DNA damage IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
bcl-2-related ovarian killer protein
Names
BCL2-related ovarian killer
BOK, BCL2 family apoptosis regulator

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204706.2 → NP_990037.1  bcl-2-related ovarian killer protein

    See identical proteins and their annotated locations for NP_990037.1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000240
    UniProtKB/Swiss-Prot
    Q9DGJ5, Q9I8I2
    Conserved Domains (1) summary
    cd06845
    Location:37 → 178
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052540.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    4744672..4764408
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046898310.1 → XP_046754266.1  bcl-2-related ovarian killer protein isoform X1

    UniProtKB/Swiss-Prot
    Q9DGJ5, Q9I8I2
    Related
    ENSGALP00010034787.1, ENSGALT00010057196.1

  2. XM_046898316.1 → XP_046754272.1  bcl-2-related ovarian killer protein isoform X3

    Conserved Domains (1) summary
    cd06845
    Location:37 → 172
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...

  3. XM_046898311.1 → XP_046754267.1  bcl-2-related ovarian killer protein isoform X1

    UniProtKB/Swiss-Prot
    Q9DGJ5, Q9I8I2

  4. XM_046898312.1 → XP_046754268.1  bcl-2-related ovarian killer protein isoform X1

    UniProtKB/Swiss-Prot
    Q9DGJ5, Q9I8I2

  5. XM_046898317.1 → XP_046754273.1  bcl-2-related ovarian killer protein isoform X3

    Conserved Domains (1) summary
    cd06845
    Location:37 → 172
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...

  6. XM_046898314.1 → XP_046754270.1  bcl-2-related ovarian killer protein isoform X2

  7. XM_046898315.1 → XP_046754271.1  bcl-2-related ovarian killer protein isoform X3

    Conserved Domains (1) summary
    cd06845
    Location:37 → 172
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...

  8. XM_046898313.1 → XP_046754269.1  bcl-2-related ovarian killer protein isoform X2

  9. XM_046898318.1 → XP_046754274.1  bcl-2-related ovarian killer protein isoform X4

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052581.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4577434..4597837
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046923582.1 → XP_046779538.1  bcl-2-related ovarian killer protein isoform X3

    Conserved Domains (1) summary
    cd06845
    Location:37 → 172
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...

  2. XM_046923577.1 → XP_046779533.1  bcl-2-related ovarian killer protein isoform X1

    UniProtKB/Swiss-Prot
    Q9DGJ5, Q9I8I2

  3. XM_046923578.1 → XP_046779534.1  bcl-2-related ovarian killer protein isoform X1

    UniProtKB/Swiss-Prot
    Q9DGJ5, Q9I8I2

  4. XM_046923584.1 → XP_046779540.1  bcl-2-related ovarian killer protein isoform X3

    Conserved Domains (1) summary
    cd06845
    Location:37 → 172
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...

  5. XM_046923580.1 → XP_046779536.1  bcl-2-related ovarian killer protein isoform X2

  6. XM_046923581.1 → XP_046779537.1  bcl-2-related ovarian killer protein isoform X3

    Conserved Domains (1) summary
    cd06845
    Location:37 → 172
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...

  7. XM_046923579.1 → XP_046779535.1  bcl-2-related ovarian killer protein isoform X2

  8. XM_046923585.1 → XP_046779541.1  bcl-2-related ovarian killer protein isoform X4

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9I8I2.1 GenPept UniProtKB/Swiss-Prot:Q9I8I2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials