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C4BPM complement component 4 binding protein, membrane [ Gallus gallus (chicken) ]

Gene ID: 395384, updated on 13-Apr-2026
Official Symbol
C4BPMprovided by CGNC
Official Full Name
complement component 4 binding protein, membraneprovided by CGNC
Primary source
CGNC:49292
See related
Ensembl:ENSGALG00010027178
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
CREM; C4BPA; Cremp
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Try the new Transcripts and proteins table
See C4BPM in Genome Data Viewer
Location:
chromosome: 26
Exon count:
19
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 26 NC_052557.1 (2722621..2759934)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 26 NC_052598.1 (2692699..2729992)

Chromosome 26 - NC_052557.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107055194 Neighboring gene complement component 4 binding protein, GPI-anchored Neighboring gene uncharacterized LOC112530321 Neighboring gene complement C3b/C4b receptor 1 Neighboring gene microRNA 29b-2 Neighboring gene microRNA 29c Neighboring gene CD34 molecule Neighboring gene plexin A2 Neighboring gene microRNA 6654

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A novel chicken membrane-associated complement regulatory protein: molecular cloning and functional characterization. Inoue N, et al. J Immunol, 2001 Jan 1. PMID 11123320
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in negative regulation of complement activation, classical pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
complement component 4 binding protein, alpha chain
Names
alpha chain
complement component 4 binding protein, alpha
complement regulatory membrane protein

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204664.2 → NP_989995.1  complement component 4 binding protein, alpha chain precursor

    See identical proteins and their annotated locations for NP_989995.1

    Status: PROVISIONAL

    Source sequence(s)
    AB035592
    UniProtKB/TrEMBL
    A0A8V1A7Q8, Q9DEG0
    Related
    ENSGALP00010040167.1, ENSGALT00010065901.1
    Conserved Domains (2) summary
    cd00033
    Location:150 → 215
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA02927
    Location:11 → 276
    PHA02927; secreted complement-binding protein; Provisional

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052557.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2722621..2759934
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040652673.2 → XP_040508607.1  complement component 4 binding protein, alpha chain isoform X3

    UniProtKB/TrEMBL
    A0A8V1A7Q8, A0A8V1AF64
    Related
    ENSGALP00010040161.1, ENSGALT00010065895.1
    Conserved Domains (3) summary
    cd00033
    Location:340 → 393
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA02954
    Location:273 → 392
    PHA02954; EEV membrane glycoprotein; Provisional
    PHA02927
    Location:15 → 267
    PHA02927; secreted complement-binding protein; Provisional

  2. XM_046904089.1 → XP_046760045.1  complement component 4 binding protein, alpha chain isoform X5

    UniProtKB/TrEMBL
    A0A8V1A7Q8

  3. XM_046904088.1 → XP_046760044.1  complement component 4 binding protein, alpha chain isoform X4

    UniProtKB/TrEMBL
    A0A8V1A7Q8
    Related
    ENSGALP00010040164.1, ENSGALT00010065898.1

  4. XM_046904087.1 → XP_046760043.1  complement component 4 binding protein, alpha chain isoform X2

    UniProtKB/TrEMBL
    A0A8V1A7P8

  5. XM_015298885.4 → XP_015154371.2  complement component 4 binding protein, alpha chain isoform X1

    UniProtKB/TrEMBL
    A0A8V1A2Q9, A0A8V1A7P8
    Related
    ENSGALP00010040165.1, ENSGALT00010065899.1
    Conserved Domains (3) summary
    cd00033
    Location:349 → 402
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA02954
    Location:282 → 401
    PHA02954; EEV membrane glycoprotein; Provisional
    PHA02927
    Location:11 → 276
    PHA02927; secreted complement-binding protein; Provisional

RNA

  1. XR_001470158.4 RNA Sequence

  2. XR_006932137.1 RNA Sequence

  3. XR_005841850.2 RNA Sequence

  4. XR_003071868.3 RNA Sequence

  5. XR_001470157.4 RNA Sequence

  6. XR_005841851.2 RNA Sequence

  7. XR_005841852.2 RNA Sequence

  8. XR_005841853.2 RNA Sequence

  9. XR_005841854.2 RNA Sequence

  10. XR_001470160.4 RNA Sequence

  11. XR_003071867.3 RNA Sequence

  12. XR_006932138.1 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052598.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    2692699..2729992
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046932853.1 → XP_046788809.1  complement component 4 binding protein, alpha chain isoform X3

    UniProtKB/TrEMBL
    A0A8V1A7Q8, A0A8V1AF64

  2. XM_046932855.1 → XP_046788811.1  complement component 4 binding protein, alpha chain isoform X5

    UniProtKB/TrEMBL
    A0A8V1A7Q8

  3. XM_046932854.1 → XP_046788810.1  complement component 4 binding protein, alpha chain isoform X4

    UniProtKB/TrEMBL
    A0A8V1A7Q8

  4. XM_046932852.1 → XP_046788808.1  complement component 4 binding protein, alpha chain isoform X2

    UniProtKB/TrEMBL
    A0A8V1A7P8

  5. XM_046932851.1 → XP_046788807.1  complement component 4 binding protein, alpha chain isoform X1

    UniProtKB/TrEMBL
    A0A8V1A2Q9, A0A8V1A7P8

RNA

  1. XR_006937116.1 RNA Sequence

  2. XR_006937117.1 RNA Sequence

  3. XR_006937111.1 RNA Sequence

  4. XR_006937110.1 RNA Sequence

  5. XR_006937113.1 RNA Sequence

  6. XR_006937112.1 RNA Sequence

  7. XR_006937118.1 RNA Sequence

  8. XR_006937119.1 RNA Sequence

  9. XR_006937120.1 RNA Sequence

  10. XR_006937114.1 RNA Sequence

  11. XR_006937121.1 RNA Sequence

  12. XR_006937115.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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