CENPH centromere protein H [Gallus gallus (chicken)] - Gene

Summary

Symbol: CENPHprovided by CGNC
Full Name: centromere protein Hprovided by CGNC
Primary source: CGNC:10967
See related: Ensembl:ENSGALG00010010809
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: CENP-H
Orthologs: human mouse all
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Genomic context

Location:: chromosome: Z

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	Z	NC_052572.1 (22450686..22456853)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	Z	NC_059536.1 (22450686..22456853)

Chromosome Z - NC_052572.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The occurrence of centromere-heterochromatin associations depends on CENP-H, but not CENP-C.
Title: 3D genomic architecture reveals that neocentromeres associate with heterochromatin regions.
CENP-H-containing complex facilitates deposition of newly synthesized CENP-A into centromeric chromatin in cooperation with FACT and CHD1.
Title: CENP-H-containing complex facilitates centromere deposition of CENP-A in cooperation with FACT and CHD1.
The CENP-H-I complex may function, in part, as a marker directing CENP-A deposition to centromeres.
Title: The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.
The functional region of chicken CENP-H necessary for centromere targeting and cell viability was identified.
Title: The functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables kinetochore binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in chromosome segregation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in kinetochore assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in mitotic spindle organization	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in kinetochore	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: centromere protein H

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.