IL2RA interleukin 2 receptor subunit alpha [Gallus gallus (chicken)] - Gene

Summary

Symbol: IL2RAprovided by CGNC
Full Name: interleukin 2 receptor subunit alphaprovided by CGNC
Primary source: CGNC:4764
See related: Ensembl:ENSGALG00010006175
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	1	NC_052532.1 (4023671..4042984, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	1	NC_052573.1 (4092444..4111723, complement)

Chromosome 1 - NC_052532.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Effects of Salmonella enterica ser. Enteritidis and Heidelberg on host CD4+CD25+ regulatory T cell suppressive immune responses in chickens.
Title: Effects of Salmonella enterica ser. Enteritidis and Heidelberg on host CD4+CD25+ regulatory T cell suppressive immune responses in chickens.
chCD25 molecules could be expressed on the surface of monocytes/macrophages, thrombocytes, CD4+ and CD8+ cells as well as tissue cells
Title: Characterization of chicken interleukin 2 receptor alpha chain, a homolog to mammalian CD25.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables interleukin-2 binding	IEA Inferred from Electronic Annotation more info	PubMed
enables interleukin-2 receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: interleukin-2 receptor subunit alpha

Names: IL-2 alpha receptor; IL2 receptor alpha; interleukin 2 receptor, alpha; interleukin-2 alpha receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204596.2 → NP_989927.2 interleukin-2 receptor subunit alpha precursor

Status: PROVISIONAL

Source sequence(s)

JAENSK010000009

UniProtKB/TrEMBL

C6KHP4, Q90WJ4

Related

ENSGALP00010008666.1, ENSGALT00010014711.1

Conserved Domains (2) summary

cd00033
Location:121 → 180

CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

smart00032
Location:23 → 81

CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

4023671..4042984 complement

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GenBank, FASTA, Sequence Viewer (Graphics)