U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

BIRC8 baculoviral IAP repeat containing 8 [ Gallus gallus (chicken) ]

Gene ID: 395280, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Symbol
BIRC8provided by CGNC
Full Name
baculoviral IAP repeat containing 8provided by CGNC
Primary source
CGNC:49241
See related
Ensembl:ENSGALG00010013281
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
IAP3; XIAP; BIRC4
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 4
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (15610353..15632576, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (15643558..15665752, complement)

Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110639 Neighboring gene microRNA 6679 Neighboring gene stromal antigen 2 Neighboring gene THO complex 2 Neighboring gene glutamate ionotropic receptor AMPA type subunit 3

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in spindle microtubule IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
E3 ubiquitin-protein ligase XIAP
Names
X-linked inhibitor of apoptosis
baculoviral IAP repeat-containing 4
inhibitor of apoptosis protein 3
NP_001383070.1
NP_001383071.1
NP_989919.2
XP_040554627.1
XP_046771418.1
XP_046771419.1
XP_046771420.1
XP_046771421.1
XP_046795838.1
XP_046795839.1
XP_046795840.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001396141.1 → NP_001383070.1  E3 ubiquitin-protein ligase XIAP

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000071
    UniProtKB/TrEMBL
    A0A8V0YRF2
    Conserved Domains (4) summary
    smart00238
    Location:160 → 230
    BIR; Baculoviral inhibition of apoptosis protein repeat
    cd00022
    Location:29 → 93
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd14395
    Location:365 → 414
    UBA_BIRC4_8; UBA domain found in E3 ubiquitin-protein ligase XIAP, baculoviral IAP repeat-containing protein 8 (BIRC8) and similar proteins
    cd16714
    Location:432 → 492
    RING-HC_BIRC4_8; RING finger, HC subclass, found in E3 ubiquitin-protein ligase XIAP, baculoviral IAP repeat-containing protein 8 (BIRC8) and similar proteins

  2. NM_001396142.1 → NP_001383071.1  E3 ubiquitin-protein ligase XIAP

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000071
    UniProtKB/TrEMBL
    A0A8V0YRF2
    Conserved Domains (4) summary
    smart00238
    Location:160 → 230
    BIR; Baculoviral inhibition of apoptosis protein repeat
    cd00022
    Location:29 → 93
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd14395
    Location:365 → 414
    UBA_BIRC4_8; UBA domain found in E3 ubiquitin-protein ligase XIAP, baculoviral IAP repeat-containing protein 8 (BIRC8) and similar proteins
    cd16714
    Location:432 → 492
    RING-HC_BIRC4_8; RING finger, HC subclass, found in E3 ubiquitin-protein ligase XIAP, baculoviral IAP repeat-containing protein 8 (BIRC8) and similar proteins

  3. NM_204588.3 → NP_989919.2  E3 ubiquitin-protein ligase XIAP

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000071
    UniProtKB/TrEMBL
    A0A8V0YRF2
    Related
    ENSGALP00010018734.1, ENSGALT00010031940.1
    Conserved Domains (4) summary
    smart00238
    Location:160 → 230
    BIR; Baculoviral inhibition of apoptosis protein repeat
    cd00022
    Location:29 → 93
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd14395
    Location:365 → 414
    UBA_BIRC4_8; UBA domain found in E3 ubiquitin-protein ligase XIAP, baculoviral IAP repeat-containing protein 8 (BIRC8) and similar proteins
    cd16714
    Location:432 → 492
    RING-HC_BIRC4_8; RING finger, HC subclass, found in E3 ubiquitin-protein ligase XIAP, baculoviral IAP repeat-containing protein 8 (BIRC8) and similar proteins

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    15610353..15632576 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046939884.1 → XP_046795840.1  E3 ubiquitin-protein ligase XIAP isoform X1

    UniProtKB/TrEMBL
    A0A8V0YRF2

  2. XM_040698693.2 → XP_040554627.1  E3 ubiquitin-protein ligase XIAP isoform X1

    UniProtKB/TrEMBL
    A0A8V0YRF2
    Conserved Domains (4) summary
    smart00238
    Location:160 → 230
    BIR; Baculoviral inhibition of apoptosis protein repeat
    cd00022
    Location:29 → 93
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd14395
    Location:365 → 414
    UBA_BIRC4_8; UBA domain found in E3 ubiquitin-protein ligase XIAP, baculoviral IAP repeat-containing protein 8 (BIRC8) and similar proteins
    cd16714
    Location:432 → 492
    RING-HC_BIRC4_8; RING finger, HC subclass, found in E3 ubiquitin-protein ligase XIAP, baculoviral IAP repeat-containing protein 8 (BIRC8) and similar proteins

  3. XM_046939883.1 → XP_046795839.1  E3 ubiquitin-protein ligase XIAP isoform X1

    UniProtKB/TrEMBL
    A0A8V0YRF2

  4. XM_046939882.1 → XP_046795838.1  E3 ubiquitin-protein ligase XIAP isoform X1

    UniProtKB/TrEMBL
    A0A8V0YRF2

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    15643558..15665752 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046915465.1 → XP_046771421.1  E3 ubiquitin-protein ligase XIAP isoform X1

    UniProtKB/TrEMBL
    Q8UVF8

  2. XM_046915462.1 → XP_046771418.1  E3 ubiquitin-protein ligase XIAP isoform X1

    UniProtKB/TrEMBL
    Q8UVF8

  3. XM_046915464.1 → XP_046771420.1  E3 ubiquitin-protein ligase XIAP isoform X1

    UniProtKB/TrEMBL
    Q8UVF8

  4. XM_046915463.1 → XP_046771419.1  E3 ubiquitin-protein ligase XIAP isoform X1

    UniProtKB/TrEMBL
    Q8UVF8
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.