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Spt20 Spt20 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39522, updated on 18-Sep-2024

Summary

Official Symbol
Spt20provided by FlyBase
Official Full Name
Spt20provided by FlyBase
Primary source
FLYBASE:FBgn0036374
Locus tag
Dmel_CG17689
See related
AllianceGenome:FB:FBgn0036374
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG17689; Dmel\CG17689; dSpt20; lincRNA.S5070
Summary
Predicted to enable transcription coregulator activity. Predicted to be involved in histone acetylation and regulation of transcription by RNA polymerase II. Located in nucleus. Part of SAGA complex. Is expressed in chordotonal neurons. Orthologous to several human genes including SUPT20H (SPT20 homolog, SAGA complex component). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Spt20 in Genome Data Viewer
Location:
70B3-70B4; 3-40 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (13502707..13511541)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (13495807..13504641)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Actin binding protein 1 Neighboring gene Tondu-domain-containing Growth Inhibitor Neighboring gene Liprin-beta Neighboring gene Vacuolar protein sorting 36 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 
enables transcription coregulator activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in chromatin organization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of SAGA complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of SAGA complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of SAGA complex IEA
Inferred from Electronic Annotation
more info
 
part_of SAGA-type complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Spt20
Names
CG17689-PA
CG17689-PC
CG17689-PD
Spt20-PA
Spt20-PC
Spt20-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    13502707..13511541
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140402.5NP_648659.2  Spt20, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648659.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5U0Z4, Q9VU86
    Conserved Domains (1) summary
    pfam12090
    Location:429559
    Spt20; Spt20 family
  2. NM_001038916.3NP_001034005.2  Spt20, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001034005.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q2PDX8
    Conserved Domains (1) summary
    pfam12090
    Location:429559
    Spt20; Spt20 family
  3. NM_001300133.1NP_001287062.1  Spt20, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287062.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5U0Z4, Q9VU86
    Conserved Domains (1) summary
    pfam12090
    Location:429559
    Spt20; Spt20 family