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CASQ2 calsequestrin 2 [ Gallus gallus (chicken) ]

Gene ID: 395198, updated on 9-Jun-2019

Summary

Symbol
CASQ2provided by CGNC
Full Name
calsequestrin 2provided by CGNC
Primary source
CGNC:49209
See related
Ensembl:ENSGALG00000015018
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
CASQ1; calsequestrin-2
Orthologs

Genomic context

See CASQ2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
11
Annotation release Status Assembly Chr Location
104 current GRCg6a (GCF_000002315.5) 1 NC_006088.5 (81232635..81263367)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 1 NC_006088.4 (80446094..80476826)
102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) 1 NC_006088.3 (79886017..79916750)

Chromosome 1 - NC_006088.5Genomic Context describing neighboring genes Neighboring gene mab-21 like 3 Neighboring gene solute carrier family 22 member 15 Neighboring gene nescient helix-loop-helix 2 Neighboring gene VANGL planar cell polarity protein 1 Neighboring gene chromodomain helicase DNA binding protein 1 like Neighboring gene fatty acid amide hydrolase-like

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Calcium Regulation in the Cardiac Cell, organism-specific biosystem (from WikiPathways)
    Calcium Regulation in the Cardiac Cell, organism-specific biosystemCalcium is a common signaling mechanism, as once it enters the cytoplasm it exerts allosteric regulatory affects on many enzymes and proteins. Calcium can act in signal transduction after influx resu...

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
Z disc IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sarcoplasmic reticulum lumen IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
terminal cisterna IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
calsequestrin-2
Names
aspartactin
calsequestrin 2 (cardiac muscle)
calsequestrin homologue
calsequestrin, skeletal muscle isoform
calsequestrin-1
laminin-binding protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204526.1NP_989857.1  calsequestrin-2 precursor

    See identical proteins and their annotated locations for NP_989857.1

    Status: PROVISIONAL

    Source sequence(s)
    Y00789
    UniProtKB/Swiss-Prot
    P19204
    Related
    ENSGALP00000036165.1, ENSGALT00000036952.4
    Conserved Domains (4) summary
    cd03065
    Location:24143
    PDI_b_Calsequestrin_N; PDIb family, Calsequestrin subfamily, N-terminal TRX-fold domain; Calsequestrin is the major calcium storage protein in the sarcoplasmic reticulum (SR) of skeletal and cardiac muscle. It stores calcium ions in sufficient quantities (up to 20 mM) to allow ...
    cd03066
    Location:145246
    PDI_b_Calsequestrin_middle; PDIb family, Calsequestrin subfamily, Middle TRX-fold domain; Calsequestrin is the major calcium storage protein in the sarcoplasmic reticulum (SR) of skeletal and cardiac muscle. It stores calcium ions in sufficient quantities (up to 20 mM) to allow ...
    cd03074
    Location:247366
    PDI_b'_Calsequestrin_C; Protein Disulfide Isomerase (PDIb') family, Calsequestrin subfamily, C-terminal TRX-fold domain; Calsequestrin is the major calcium storage protein in the sarcoplasmic reticulum (SR) of skeletal and cardiac muscle. It stores calcium ions in sufficient ...
    pfam01216
    Location:22371
    Calsequestrin; Calsequestrin

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCg6a Primary Assembly

Genomic

  1. NC_006088.5 Reference GRCg6a Primary Assembly

    Range
    81232635..81263367
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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