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CRHR2 corticotropin releasing hormone receptor 2 [ Gallus gallus (chicken) ]

Gene ID: 395105, updated on 3-Dec-2024
Symbol
CRHR2provided by CGNC
Full Name
corticotropin releasing hormone receptor 2provided by CGNC
Primary source
CGNC:4214
See related
Ensembl:ENSGALG00010026229
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
CRH-R2
Orthologs
human mouse all
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See CRHR2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
16
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (4182262..4319527)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (4184291..4321565)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene myosin IG Neighboring gene GTPase, IMAP family member 6 Neighboring gene uncharacterized LOC121109644 Neighboring gene uncharacterized LOC101748313 Neighboring gene zinc finger protein 91-like Neighboring gene glycyl-tRNA synthetase

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Corticotropin-releasing hormone (CRH)-induced thyrotropin release is directly mediated through CRH receptor type 2 on thyrotropes. De Groef B, et al. Endocrinology, 2003 Dec. PMID 12970166
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled peptide receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables corticotrophin-releasing factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables corticotropin-releasing hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptide hormone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in long-term synaptic potentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon terminus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
corticotropin-releasing factor receptor 2
Names
putative corticotropin-releasing hormone receptor type 2

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204454.2 → NP_989785.2  corticotropin-releasing factor receptor 2

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000035
    UniProtKB/TrEMBL
    F1NGG4, Q7ZZZ2
    Related
    ENSGALP00010039354.1, ENSGALT00010063838.1
    Conserved Domains (2) summary
    smart00008
    Location:39 → 109
    HormR; Domain present in hormone receptors
    cd15446
    Location:114 → 377
    7tmB1_CRF-R2; corticotropin-releasing factor receptor 2, member of the class B family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    4182262..4319527
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015281045.4 → XP_015136531.2  corticotropin-releasing factor receptor 2 isoform X2

    UniProtKB/TrEMBL
    A0A2Z2GYS6
    Related
    ENSGALP00010039362.1, ENSGALT00010063854.1
    Conserved Domains (2) summary
    smart00008
    Location:53 → 124
    HormR; Domain present in hormone receptors
    cd15446
    Location:129 → 392
    7tmB1_CRF-R2; corticotropin-releasing factor receptor 2, member of the class B family of seven-transmembrane G protein-coupled receptors

  2. XM_040674883.2 → XP_040530817.1  corticotropin-releasing factor receptor 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V1AAR7
    Related
    ENSGALP00010039358.1, ENSGALT00010063845.1
    Conserved Domains (3) summary
    smart00008
    Location:55 → 126
    HormR; Domain present in hormone receptors
    cd14964
    Location:133 → 158
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:131 → 384
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  3. XM_040674890.1 → XP_040530824.1  corticotropin-releasing factor receptor 2 isoform X4

    UniProtKB/TrEMBL
    A0A8V1A812
    Conserved Domains (2) summary
    cd15446
    Location:91 → 354
    7tmB1_CRF-R2; corticotropin-releasing factor receptor 2, member of the class B family of seven-transmembrane G protein-coupled receptors
    cl02422
    Location:55 → 86
    HRM; Hormone receptor domain

  4. XM_040674867.1 → XP_040530801.1  corticotropin-releasing factor receptor 2 isoform X1

    UniProtKB/TrEMBL
    A0A2Z2GYS6
    Conserved Domains (2) summary
    smart00008
    Location:55 → 126
    HormR; Domain present in hormone receptors
    cd15446
    Location:131 → 394
    7tmB1_CRF-R2; corticotropin-releasing factor receptor 2, member of the class B family of seven-transmembrane G protein-coupled receptors

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4184291..4321565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046910265.1 → XP_046766221.1  corticotropin-releasing factor receptor 2 isoform X2

    UniProtKB/TrEMBL
    A0A2Z2GYS6

  2. XM_046910266.1 → XP_046766222.1  corticotropin-releasing factor receptor 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V1AAR7

  3. XM_046910267.1 → XP_046766223.1  corticotropin-releasing factor receptor 2 isoform X4

    UniProtKB/TrEMBL
    A0A8V1A812

  4. XM_046910264.1 → XP_046766220.1  corticotropin-releasing factor receptor 2 isoform X1

    UniProtKB/TrEMBL
    A0A2Z2GYS6
Nucleotide Protein
Heading Accession and Version

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