hmgb1 high mobility group box 1 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: hmgb1provided by Xenbase
Official Full Name: high mobility group box 1provided by Xenbase
Primary source: Xenbase:XB-GENE-1001206
See related: Ensembl:ENSXETG00000019166 AllianceGenome:Xenbase:XB-GENE-1001206
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: hmg1; hmg3; hmg-1; sbp-1
Summary: Predicted to enable DNA binding activity, bending. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromosome and nucleus. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis and congestive heart failure. Orthologous to several human genes including HMGB1 (high mobility group box 1). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 2

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	2	NC_030678.2 (154159196..154168037)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	2	NC_030678.1 (151195400..151204216)

Chromosome 2 - NC_030678.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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General protein information

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Preferred Names: high mobility group protein B1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.