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folr1 folate receptor alpha [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 394697, updated on 9-Dec-2024

Summary

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Official Symbol
folr1provided by Xenbase
Official Full Name
folate receptor alphaprovided by Xenbase
Primary source
Xenbase:XB-GENE-948101
See related
Ensembl:ENSXETG00000044118 AllianceGenome:Xenbase:XB-GENE-948101
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
fbp; folr; FRalpha
Summary
Human ortholog(s) of this gene implicated in cerebral folate receptor alpha deficiency. Orthologous to several human genes including FOLR1 (folate receptor alpha); FOLR2 (folate receptor beta); and FOLR3 (folate receptor gamma). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See folr1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
8
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (178952554..178962777)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016684165.1 (9131..17642)

Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene secreted frizzled-related protein Neighboring gene transmembrane O-methyltransferase homolog Neighboring gene inositol polyphosphate phosphatase-like 1a Neighboring gene paired like homeobox 2A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC76048

General protein information

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Preferred Names
folate receptor alpha
Names
folate receptor 1 (adult)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_203762.1 → NP_989093.1  folate receptor alpha precursor

    See identical proteins and their annotated locations for NP_989093.1

    Status: PROVISIONAL

    Source sequence(s)
    BC062496
    UniProtKB/TrEMBL
    Q6P638
    Conserved Domains (1) summary
    pfam03024
    Location:24 → 199
    Folate_rec; Folate receptor family

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    178952554..178962777
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018090504.2 → XP_017945993.2  folate receptor alpha isoform X4

    UniProtKB/TrEMBL
    A0A8J0T0C1
    Conserved Domains (1) summary
    pfam03024
    Location:29 → 204
    Folate_rec; Folate receptor family

  2. XM_018090503.2 → XP_017945992.2  folate receptor alpha isoform X3

    UniProtKB/TrEMBL
    A0A8J0SQV7
    Conserved Domains (1) summary
    pfam03024
    Location:37 → 212
    Folate_rec; Folate receptor family

  3. XM_018090502.2 → XP_017945991.2  folate receptor alpha isoform X2

    UniProtKB/TrEMBL
    F7CGN2
    Related
    ENSXETP00000051710.5, ENSXETT00000051710.5
    Conserved Domains (1) summary
    pfam03024
    Location:39 → 214
    Folate_rec; Folate receptor family

  4. XM_018090501.2 → XP_017945990.2  folate receptor alpha isoform X1

    UniProtKB/TrEMBL
    A0A8J0T128
    Conserved Domains (1) summary
    pfam03024
    Location:68 → 243
    Folate_rec; Folate receptor family
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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