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hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase [ Danio rerio (zebrafish) ]

Gene ID: 394190, updated on 14-Feb-2019

Summary

Official Symbol
hmgclprovided by ZNC
Official Full Name
3-hydroxy-3-methylglutaryl-CoA lyaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-958
See related
Ensembl:ENSDARG00000021220
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
zgc:56248
Orthologs

Genomic context

See hmgcl in Genome Data Viewer
Location:
chromosome: 17
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (24855678..24866727, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (24837277..24848326, complement)
103 previous assembly Zv9 (GCF_000002035.4) 17 NC_007128.5 (24683835..24694884, complement)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene connexin 34.4 Neighboring gene connexin 35.4 Neighboring gene zinc finger and BTB domain containing 8A Neighboring gene UDP-galactose-4-epimerase

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

Clone Names

  • MGC56248

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
hydroxymethylglutaryl-CoA lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hydroxymethylglutaryl-CoA lyase activity IEA
Inferred from Electronic Annotation
more info
 
lyase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
ketone body biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
leucine catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
hydroxymethylglutaryl-CoA lyase, mitochondrial
Names
3-hydroxymethyl-3-methylglutaryl-CoA lyase
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)
NP_957509.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201215.1NP_957509.1  hydroxymethylglutaryl-CoA lyase, mitochondrial

    See identical proteins and their annotated locations for NP_957509.1

    Status: PROVISIONAL

    Source sequence(s)
    BC046023
    UniProtKB/TrEMBL
    Q7ZV32
    Related
    ENSDARP00000026028.7, ENSDART00000027957.8
    Conserved Domains (2) summary
    cd07938
    Location:50323
    DRE_TIM_HMGL; 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain
    pfam00682
    Location:47321
    HMGL-like; HMGL-like

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    24855678..24866727 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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