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ercc2 excision repair cross-complementation group 2 [ Danio rerio (zebrafish) ]

Gene ID: 393900, updated on 17-Nov-2020

Summary

Official Symbol
ercc2provided by ZNC
Official Full Name
excision repair cross-complementation group 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-997
See related
Ensembl:ENSDARG00000021985
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
XP; XPD; zgc:56365
Orthologs

Genomic context

See ercc2 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
23
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (23680018..23692359, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (23744753..23757094, complement)
103 previous assembly Zv9 (GCF_000002035.4) 15 NC_007126.5 (23033564..23045907, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene creatine kinase, muscle b Neighboring gene kinesin light chain 3 Neighboring gene zgc:154093 Neighboring gene zinc finger CCCH-type containing 4

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC56365

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
damaged DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
helicase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEA
Inferred from Electronic Annotation
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
nucleobase-containing compound metabolic process IEA
Inferred from Electronic Annotation
more info
 
nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
 
nucleotide-excision repair, DNA duplex unwinding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleotide-excision repair, DNA incision IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of mitotic recombination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to UV IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to oxidative stress IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
general transcription and DNA repair factor IIH helicase subunit XPD
Names
excision repair cross-complementing rodent repair deficiency, complementation group 2
NP_957220.2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200926.2NP_957220.2  general transcription and DNA repair factor IIH helicase subunit XPD

    See identical proteins and their annotated locations for NP_957220.2

    Status: VALIDATED

    Source sequence(s)
    CR855332, EH550017, EH589655, EH607129
    UniProtKB/TrEMBL
    F1Q5E7
    Related
    ENSDARP00000114026.1, ENSDART00000141618.2
    Conserved Domains (4) summary
    smart00488
    Location:8278
    DEXDc2; DEAD-like helicases superfamily
    smart00491
    Location:542686
    HELICc2; helicase superfamily c-terminal domain
    TIGR00604
    Location:7708
    rad3; DNA repair helicase (rad3)
    pfam06777
    Location:270413
    HBB; Helical and beta-bridge domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    23680018..23692359 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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