Format

Send to:

Choose Destination

cdc14b cell division cycle 14B [ Danio rerio (zebrafish) ]

Gene ID: 393148, updated on 22-Nov-2020

Summary

Official Symbol
cdc14bprovided by ZNC
Official Full Name
cell division cycle 14Bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-820
See related
Ensembl:ENSDARG00000021483
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cdc14; cdc14a; zgc:55844
Orthologs

Genomic context

See cdc14b in Genome Data Viewer
Location:
chromosome: 8
Exon count:
19
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (1222130..1267306, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (1156389..1201687, complement)
103 previous assembly Zv9 (GCF_000002035.4) 8 NC_007119.5 (1290801..1336007, complement)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 35 member D2 Neighboring gene zinc finger protein 367 Neighboring gene peroxiredoxin like 2C Neighboring gene F-box and leucine-rich repeat protein 17

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC55844

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein tyrosine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
protein tyrosine/serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cilium assembly IGI
Inferred from Genetic Interaction
more info
PubMed 
cilium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitotic cell cycle arrest IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of cytokinesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
regulation of exit from mitosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
NOT centrosome IDA
Inferred from Direct Assay
more info
PubMed 
NOT ciliary basal body IDA
Inferred from Direct Assay
more info
PubMed 
condensed chromosome IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
mitotic spindle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
spindle IDA
Inferred from Direct Assay
more info
PubMed 
spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
dual specificity protein phosphatase CDC14B
Names
CDC14 cell division cycle 14 homolog A
CDC14 cell division cycle 14 homolog B
NP_956473.1
XP_005166727.1
XP_005166728.1
XP_005166729.1
XP_005166730.1
XP_021333883.1
XP_021333884.1
XP_021333885.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200179.1NP_956473.1  dual specificity protein phosphatase CDC14B

    See identical proteins and their annotated locations for NP_956473.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045476
    UniProtKB/TrEMBL
    Q7ZVN3
    Related
    ENSDARP00000154397.1, ENSDART00000190371.1
    Conserved Domains (2) summary
    pfam14671
    Location:193
    DSPn; Dual specificity protein phosphatase, N-terminal half
    cl21483
    Location:128267
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    1222130..1267306 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021478208.1XP_021333883.1  dual specificity protein phosphatase CDC14B isoform X1

    Conserved Domains (2) summary
    pfam14671
    Location:29166
    DSPn; Dual specificity protein phosphatase, N-terminal half
    cl21483
    Location:200339
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
  2. XM_005166670.4XP_005166727.1  dual specificity protein phosphatase CDC14B isoform X1

    See identical proteins and their annotated locations for XP_005166727.1

    Conserved Domains (2) summary
    pfam14671
    Location:29166
    DSPn; Dual specificity protein phosphatase, N-terminal half
    cl21483
    Location:200339
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
  3. XM_005166672.4XP_005166729.1  dual specificity protein phosphatase CDC14B isoform X3

    Conserved Domains (2) summary
    pfam14671
    Location:31165
    DSPn; Dual specificity protein phosphatase, N-terminal half
    cl21483
    Location:200339
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
  4. XM_005166673.4XP_005166730.1  dual specificity protein phosphatase CDC14B isoform X4

    UniProtKB/TrEMBL
    F8W2B2
    Related
    ENSDARP00000124791.1, ENSDART00000150064.3
    Conserved Domains (2) summary
    pfam14671
    Location:31165
    DSPn; Dual specificity protein phosphatase, N-terminal half
    cl21483
    Location:200339
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
  5. XM_005166671.4XP_005166728.1  dual specificity protein phosphatase CDC14B isoform X2

    Conserved Domains (2) summary
    pfam14671
    Location:20154
    DSPn; Dual specificity protein phosphatase, N-terminal half
    cl21483
    Location:189328
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
  6. XM_021478209.1XP_021333884.1  dual specificity protein phosphatase CDC14B isoform X5

    Conserved Domains (2) summary
    pfam14671
    Location:29166
    DSPn; Dual specificity protein phosphatase, N-terminal half
    cl21483
    Location:200339
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
  7. XM_021478210.1XP_021333885.1  dual specificity protein phosphatase CDC14B isoform X6

    Related
    ENSDARP00000124917.1, ENSDART00000149924.3
    Conserved Domains (2) summary
    pfam14671
    Location:18155
    DSPn; Dual specificity protein phosphatase, N-terminal half
    cl21483
    Location:189328
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
Support Center