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mycb MYC proto-oncogene, bHLH transcription factor b [ Danio rerio (zebrafish) ]

Gene ID: 393141, updated on 26-May-2019

Summary

Official Symbol
mycbprovided by ZNC
Official Full Name
MYC proto-oncogene, bHLH transcription factor bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-780
See related
Ensembl:ENSDARG00000007241
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
zgc:55680

Genomic context

See mycb in Genome Data Viewer
Location:
chromosome: 2
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (32016281..32018371)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (32033063..32035153)
103 previous assembly Zv9 (GCF_000002035.4) 2 NC_007113.5 (31734156..31736246)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene OTU deubiquitinase with linear linkage specificity b Neighboring gene ANKH inorganic pyrophosphate transport regulator b Neighboring gene si:ch211-139k8.2 Neighboring gene uncharacterized LOC100003868

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

Clone Names

  • MGC55680

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific ISS
Inferred from Sequence or Structural Similarity
more info
 
RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
definitive hemopoiesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
hematopoietic progenitor cell differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
hematopoietic progenitor cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transcriptional regulator Myc-B
Names
C-Myc2
c-Myc-B
cmycb
myelocytomatosis oncogene b
v-myc avian myelocytomatosis viral oncogene homolog b

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200172.1NP_956466.1  transcriptional regulator Myc-B

    See identical proteins and their annotated locations for NP_956466.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045424
    UniProtKB/Swiss-Prot
    Q7ZVS9
    UniProtKB/TrEMBL
    B2GQB7
    Related
    ENSDARP00000010970.5, ENSDART00000005143.6
    Conserved Domains (3) summary
    cd00083
    Location:311370
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam01056
    Location:6304
    Myc_N; Myc amino-terminal region
    pfam02344
    Location:368396
    Myc-LZ; Myc leucine zipper domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    32016281..32018371
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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