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Sod1 Superoxide dismutase 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39251, updated on 5-Mar-2017
Official Symbol
Sod1provided by FlyBase
Official Full Name
Superoxide dismutase 1provided by FlyBase
Primary source
FLYBASE:FBgn0003462
Locus tag
Dmel_CG11793
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11793; cSod; cSOD; Cu; Cu-Zn SOD; Cu/Zn sod; Cu/Zn SOD; Cu/Zn superoxide dismutase; Cu/ZnSOD; CuSOD; CuZn SOD; CuZn-SOD; CuZn-SOD1; CuZnSOD; Cu[2+]/Zn[2+]SOD; Dmel\CG11793; dSOD1; G; l(3)108; l(3)68Af'; l(3)G; Mn SOD; sod; Sod; SOD; Sod-1; SOD-1; sod1; SOD1; SODC_DROME; To; To-1; Zn Sod; Zn SOD; Zn-SOD; ZnSod
Location:
68A7-68A7
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11112281..11113740, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11105381..11106840, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene CG34012 gene product from transcript CG34012-RA Neighboring gene CG7638 gene product from transcript CG7638-RA Neighboring gene Forkhead box K Neighboring gene mitochondrial ribosomal protein L2 Neighboring gene Ubiquitin fusion-degradation 1-like

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Longevity regulating pathway - multiple species, organism-specific biosystem (from KEGG)
    Longevity regulating pathway - multiple species, organism-specific biosystemAging is a complex process of accumulation of molecular, cellular, and organ damage, leading to loss of function and increased vulnerability to disease and death. Despite the complexity of aging, rec...
  • Longevity regulating pathway - multiple species, conserved biosystem (from KEGG)
    Longevity regulating pathway - multiple species, conserved biosystemAging is a complex process of accumulation of molecular, cellular, and organ damage, leading to loss of function and increased vulnerability to disease and death. Despite the complexity of aging, rec...
  • Peroxisome, organism-specific biosystem (from KEGG)
    Peroxisome, organism-specific biosystemPeroxisomes are essential organelles that play a key role in redox signalling and lipid homeostasis. They contribute to many crucial metabolic processes such as fatty acid oxidation, biosynthesis of ...
  • Peroxisome, conserved biosystem (from KEGG)
    Peroxisome, conserved biosystemPeroxisomes are essential organelles that play a key role in redox signalling and lipid homeostasis. They contribute to many crucial metabolic processes such as fatty acid oxidation, biosynthesis of ...
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
antioxidant activity NAS
Non-traceable Author Statement
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
superoxide dismutase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
age-dependent response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
aging TAS
Traceable Author Statement
more info
PubMed 
determination of adult lifespan IMP
Inferred from Mutant Phenotype
more info
PubMed 
determination of adult lifespan TAS
Traceable Author Statement
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
regulation of mitophagy IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of terminal button organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
superoxide metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
peroxisome IDA
Inferred from Direct Assay
more info
PubMed 
peroxisome ISM
Inferred from Sequence Model
more info
PubMed 
peroxisome ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Preferred Names
CG11793 gene product from transcript CG11793-RA
Names
CG11793-PA
CG11793-PD
Cu, Zn superoxide dismutase
Cu-Zn superoxide dismutase
Cu/Zn superoxide dismutase
Cu/Zn-Superoxide dismutase
CuZn superoxide dismutase
CuZn-superoxide dismutase
CuZn-superoxide dismutase (SOD)1
CuZnSOD
Cu[2+] Zn[2+] superoxide dismutase
Cu[2+]Zn[2+] superoxide dismutase
Mn superoxide dismutase
Sod1-PA
Sod1-PD
complementation group G
copper and zinc SOD
copper-zinc superoxide
copper-zinc superoxide dismutase
cytoplasmic Cu/ZnSOD
dismutase
heart morphogenesis; GO:0003007 | IMP
paracrine signaling; GO:0038001 | IMP
reactive oxygen species metabolic process; GO:0072593 | IMP
super oxide dismutase
superoxidase dismutase
superoxide dismutase
superoxide dismutase 1
superoxide dismutatase
superoxide-dismutase
superoxido dismutase
tetrazolium oxidase
tetrazolium oxidase-1
NP_001261700.1
NP_476735.1

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    11112281..11113740 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_057387.5NP_476735.1  superoxide dismutase 1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476735.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P61851
    Related
    FBpp0075958, FBtr0076229
    Conserved Domains (1) summary
    cl00891
    Location:2150
    Cu-Zn_Superoxide_Dismutase; Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the ...
  2. NM_001274771.1NP_001261700.1  superoxide dismutase 1, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261700.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PF91
    Related
    FBpp0305736, FBtr0333559
    Conserved Domains (1) summary
    cl00891
    Location:2164
    Cu-Zn_Superoxide_Dismutase; Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the ...
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