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OR1L6 olfactory receptor family 1 subfamily L member 6 [ Homo sapiens (human) ]

Gene ID: 392390, updated on 22-Sep-2022

Summary

Official Symbol
OR1L6provided by HGNC
Official Full Name
olfactory receptor family 1 subfamily L member 6provided by HGNC
Primary source
HGNC:HGNC:8218
See related
Ensembl:ENSG00000171459 AllianceGenome:HGNC:8218
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HG16; OR1K1; OR1L7; OR9-30
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR1L6 in Genome Data Viewer
Location:
9q33.2
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (122742303..122750783)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (134939628..134948109)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (125504582..125513062)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene tousled like kinase 1 pseudogene 1 Neighboring gene olfactory receptor family 1 subfamily L member 4 Neighboring gene spindle and kinetochore associated complex subunit 2 pseudogene 1 Neighboring gene olfactory receptor family 5 subfamily C member 1

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
olfactory receptor 1L6
Names
olfactory receptor 1L7
olfactory receptor OR9-30
olfactory receptor, family 1, subfamily L, member 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_034003.1 RefSeqGene

    Range
    5001..5936
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001004453.3NP_001004453.2  olfactory receptor 1L6

    See identical proteins and their annotated locations for NP_001004453.2

    Status: VALIDATED

    Source sequence(s)
    AC006313
    Consensus CDS
    CCDS35130.2
    UniProtKB/Swiss-Prot
    Q8NGR2
    UniProtKB/TrEMBL
    A0A0C4DFP2
    Related
    ENSP00000304235.2, ENST00000304720.3
    Conserved Domains (2) summary
    pfam00001
    Location:42291
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:32305
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    122742303..122750783
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    134939628..134948109
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)