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CTSL3P cathepsin L family member 3, pseudogene [ Homo sapiens (human) ]

Gene ID: 392360, updated on 22-May-2022

Summary

Official Symbol
CTSL3Pprovided by HGNC
Official Full Name
cathepsin L family member 3, pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:33132
See related
Ensembl:ENSG00000188029 AllianceGenome:HGNC:33132
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CTSL3; HCTSL-s
Summary
Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in cellular protein catabolic process. Predicted to be active in extracellular space and lysosome. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

See CTSL3P in Genome Data Viewer
Location:
9q21.33
Exon count:
5
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (87772915..87786884)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (99926316..99940266)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (90387830..90401799)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3 subunit J pseudogene Neighboring gene uncharacterized LOC124902198 Neighboring gene CRISPRi-validated cis-regulatory element chr9.1075 Neighboring gene Sharpr-MPRA regulatory region 3109

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Other Names

  • cathepsin L-like protein

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in proteolysis involved in protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in lysosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_027917.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AJ851862, AL160279
    Related
    ENST00000354530.2

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    87772915..87786884
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    99926316..99940266
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001023564.2: Suppressed sequence

    Description
    NM_001023564.2: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.