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SAOUHSC_00233 antiholin-like protein LrgB [ Staphylococcus aureus subsp. aureus NCTC 8325 ]

Gene ID: 3920308, updated on 30-Jan-2018

Summary

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Gene symbol
SAOUHSC_00233
Gene description
antiholin-like protein LrgB
Locus tag
SAOUHSC_00233
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Staphylococcus aureus subsp. aureus NCTC 8325 (strain: NCTC 8325, sub-species: aureus)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus
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Genomic context

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Sequence:
NC_007795.1 (254558..255259)

NC_007795.1Genomic Context describing neighboring genes Neighboring gene two-component sensor histidine kinase Neighboring gene two-component response regulator Neighboring gene murein hydrolase regulator LrgA Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007795.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Inactivation of the Autolysis-Related Genes lrgB and yycI in Staphylococcus aureus Increases Cell Lysis-Dependent eDNA Release and Enhances Biofilm Development In Vitro and In Vivo. Beltrame CO, et al. PLoS One, 2015. PMID 26406329, Free PMC Article
  2. Identification of LytSR-regulated genes from Staphylococcus aureus. Brunskill EW, et al. J Bacteriol, 1996 Oct. PMID 8824633, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Results show that lrgB and yycI are important biofilm modulators and autolytic mechanisms. Also, inactivation of lrgB or yycI results in increased virulence in a murine foreign-body infection model.
    Title: Inactivation of the Autolysis-Related Genes lrgB and yycI in Staphylococcus aureus Increases Cell Lysis-Dependent eDNA Release and Enhances Biofilm Development In Vitro and In Vivo.
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General gene information

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Homology

General protein information

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Names
antiholin-like protein LrgB
YP_498828.1
  • in conjunction with LrgA this protein inhibits the expression or activity of extracellular murein hydrolases

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007795.1 Reference assembly

    Range
    254558..255259
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_498828.1 antiholin-like protein LrgB [Staphylococcus aureus subsp. aureus NCTC 8325]

    See identical proteins and their annotated locations for YP_498828.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P60643
    Conserved Domains (1) summary
    PRK04288
    Location:2 → 214
    PRK04288; antiholin-like protein LrgB; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P60643.1

Gene LinkOut

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