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TRIM75 tripartite motif containing 75 [ Homo sapiens (human) ]

Gene ID: 391714, updated on 25-Nov-2021

Summary

Official Symbol
TRIM75provided by HGNC
Official Full Name
tripartite motif containing 75provided by HGNC
Primary source
HGNC:HGNC:32686
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TRIM75P
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Genomic context

See TRIM75 in Genome Data Viewer
Location:
4q32.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (165053866..165060554)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (165980120..165981714)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene tripartite motif-containing 75 pseudogene Neighboring gene tripartite motif containing 60 Neighboring gene transmembrane protein 192 Neighboring gene kelch like family member 2 Neighboring gene RNA, U4 small nuclear 87, pseudogene

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in female meiosis I ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular space HDA PubMed 

General protein information

Preferred Names
putative tripartite motif-containing protein 75
Names
tripartite motif containing 75, pseudogene
tripartite motif-containing protein 75
tripartite motif-containing protein 75 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001396070.1NP_001382999.1  putative tripartite motif-containing protein 75

    Status: VALIDATED

    Source sequence(s)
    AC106872, AC108465
    Conserved Domains (4) summary
    COG4942
    Location:127233
    EnvC; Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]
    cd15829
    Location:276462
    SPRY_PRY_TRIM75; PRY/SPRY domain of tripartite motif-binding protein 75 (TRIM75)
    cd16590
    Location:1357
    RING-HC_TRIM4_C-IV_like; RING finger, HC subclass, found in tripartite motif-containing proteins, TRIM4, TRIM75, tripartite motif family-like protein 1 (TRIML1) and similar proteins
    cd19791
    Location:95133
    Bbox2_TRIM60-like; B-box-type 2 zinc finger found in tripartite motif-containing proteins, TRIM60, TRIM61, TRIM75 and similar proteins

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    165053866..165060554
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_016722.1: Suppressed sequence

    Description
    NG_016722.1: This RefSeq was removed because it is now thought that this gene does encode a protein.
  2. NM_001105575.1: Suppressed sequence

    Description
    NM_001105575.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
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