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OR2M7 olfactory receptor family 2 subfamily M member 7 [ Homo sapiens (human) ]

Gene ID: 391196, updated on 11-Jun-2021

Summary

Official Symbol
OR2M7provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily M member 7provided by HGNC
Primary source
HGNC:HGNC:19594
See related
Ensembl:ENSG00000177186 MIM:618509
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR1-58
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR2M7 in Genome Data Viewer
Location:
1q44
Exon count:
1
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (248323630..248324568, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (248486932..248487870, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily T member 33 Neighboring gene olfactory receptor family 2 subfamily T member 12 Neighboring gene olfactory receptor family 14 subfamily C member 36 Neighboring gene olfactory receptor family 2 subfamily T member 4

Genomic regions, transcripts, and products

Bibliography

Related articles in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Web-based, participant-driven studies yield novel genetic associations for common traits.
GeneReviews: Not available

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 2M7
Names
OR2M7 D
OR2M7 N
OR2M7 O
olfactory receptor OR1-58

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004691.1NP_001004691.1  olfactory receptor 2M7

    See identical proteins and their annotated locations for NP_001004691.1

    Status: PROVISIONAL

    Source sequence(s)
    AL450303
    Consensus CDS
    CCDS31111.1
    UniProtKB/Swiss-Prot
    Q8NG81
    UniProtKB/TrEMBL
    A0A126GVZ1
    Related
    ENSP00000324557.2, ENST00000317965.3
    Conserved Domains (1) summary
    cd15421
    Location:25301
    7tmA_OR2T-like; olfactory receptor subfamily 2T and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    248323630..248324568 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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