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OR2L3 olfactory receptor family 2 subfamily L member 3 [ Homo sapiens (human) ]

Gene ID: 391192, updated on 22-Sep-2022

Summary

Official Symbol
OR2L3provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily L member 3provided by HGNC
Primary source
HGNC:HGNC:15009
See related
Ensembl:ENSG00000198128 AllianceGenome:HGNC:15009
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR2L3 in Genome Data Viewer
Location:
1q44
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (248046836..248063407)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (247472888..247489460)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (248210138..248226709)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily L member 13 Neighboring gene olfactory receptor family 2 subfamily L member 5 Neighboring gene uncharacterized LOC105373275 Neighboring gene olfactory receptor family 2 subfamily L member 2 Neighboring gene olfactory receptor family 2 subfamily T member 32 pseudogene Neighboring gene olfactory receptor family 2 subfamily M member 1 pseudogene

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in biological_process ND
No biological Data available
more info
 
involved_in detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004687.2NP_001004687.1  olfactory receptor 2L3

    See identical proteins and their annotated locations for NP_001004687.1

    Status: VALIDATED

    Source sequence(s)
    AC099570
    Consensus CDS
    CCDS31104.1
    UniProtKB/Swiss-Prot
    B9EH44, Q8NG85
    Related
    ENSP00000353044.3, ENST00000359959.4
    Conserved Domains (2) summary
    pfam00001
    Location:40289
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:32303
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    248046836..248063407
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    247472888..247489460
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)