U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

VSIG8 V-set and immunoglobulin domain containing 8 [ Homo sapiens (human) ]

Gene ID: 391123, updated on 10-Dec-2024

Summary

Official Symbol
VSIG8provided by HGNC
Official Full Name
V-set and immunoglobulin domain containing 8provided by HGNC
Primary source
HGNC:HGNC:32063
See related
Ensembl:ENSG00000243284 AllianceGenome:HGNC:32063
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Enables RNA binding activity. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in skin (RPKM 5.5), kidney (RPKM 1.8) and 4 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See VSIG8 in Genome Data Viewer
Location:
1q23.2
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (159854316..159862657, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (158991321..158999665, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (159824106..159832447, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene SLAM family member 8 Neighboring gene small nucleolar RNA host gene 28 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:159815652-159816152 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:159816153-159816653 Neighboring gene small nucleolar RNA SNORD64 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1455 Neighboring gene uncharacterized LOC107985216 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:159830948-159831862 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:159831863-159832775 Neighboring gene Sharpr-MPRA regulatory region 5062 Neighboring gene cilia and flagella associated protein 45 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:159859176-159860375 Neighboring gene uncharacterized LOC124904434 Neighboring gene microRNA 4259

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
V-set and immunoglobulin domain-containing protein 8

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013661.1NP_001013683.1  V-set and immunoglobulin domain-containing protein 8 precursor

    See identical proteins and their annotated locations for NP_001013683.1

    Status: VALIDATED

    Source sequence(s)
    AL590560
    Consensus CDS
    CCDS30913.1
    UniProtKB/Swiss-Prot
    P0DPA2
    Related
    ENSP00000357080.1, ENST00000368100.1
    Conserved Domains (2) summary
    smart00410
    Location:160256
    IG_like; Immunoglobulin like
    pfam07686
    Location:35142
    V-set; Immunoglobulin V-set domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    159854316..159862657 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    158991321..158999665 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)