Or67a Odorant receptor 67a [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Or67aprovided by FlyBase
Official Full Name: Odorant receptor 67aprovided by FlyBase
Primary source: FLYBASE:FBgn0036009
Locus tag: Dmel_CG12526
See related: AllianceGenome:FB:FBgn0036009
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 67a; 67B.1; CG12526; DmelOr67a.P; Dmel\CG12526; DmOr67a; DmOR67a; DOR84; OR67a
Summary: Enables odorant binding activity. Involved in detection of chemical stimulus involved in sensory perception of smell. Located in plasma membrane. Is expressed in adult olfactory receptor neuron Or67a; antennal basiconic sensillum ab10; and antennal lobe glomerulus DM6. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (9529067..9531386)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (9522167..9524486)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

we show that insect ORs(DmOR67a, DmOR85b and DmORCO) and their co-receptor can be expressed in an E. coli cell-free system
Title: Cell-free expression, purification, and ligand-binding analysis of Drosophila melanogaster olfactory receptors DmOR67a, DmOR85b and DmORCO.

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables ionotropic olfactory receptor activity	HDA more info	PubMed
enables odorant binding	IEA Inferred from Electronic Annotation more info
enables odorant binding	IPI Inferred from Physical Interaction more info	PubMed
enables odorant binding	ISS Inferred from Sequence or Structural Similarity more info
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables olfactory receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in detection of chemical stimulus involved in sensory perception of smell	HDA more info	PubMed
involved_in detection of chemical stimulus involved in sensory perception of smell	IBA Inferred from Biological aspect of Ancestor more info
involved_in sensory perception of smell	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in dendrite membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	HDA more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info