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ZNF805 zinc finger protein 805 [ Homo sapiens (human) ]

Gene ID: 390980, updated on 13-Mar-2020

Summary

Official Symbol
ZNF805provided by HGNC
Official Full Name
zinc finger protein 805provided by HGNC
Primary source
HGNC:HGNC:23272
See related
Ensembl:ENSG00000204524
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in bone marrow (RPKM 2.1), spleen (RPKM 1.2) and 25 other tissues See more
Orthologs

Genomic context

See ZNF805 in Genome Data Viewer
Location:
19q13.43
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (57240632..57262728)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (57752053..57774106)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 264 Neighboring gene aurora kinase C Neighboring gene Sharpr-MPRA regulatory region 2652 Neighboring gene ZNF460 antisense RNA 1 Neighboring gene zinc finger protein 460 Neighboring gene PPPDE peptidase domain containing 1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp686P08106

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 805
Names
CTC-444N24.8

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001023563.4NP_001018857.2  zinc finger protein 805 isoform 1

    See identical proteins and their annotated locations for NP_001018857.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC005261
    Consensus CDS
    CCDS46207.1
    UniProtKB/Swiss-Prot
    Q5CZA5
    Related
    ENSP00000412999.1, ENST00000414468.3
    Conserved Domains (6) summary
    smart00349
    Location:1373
    KRAB; krueppel associated box
    COG5048
    Location:192568
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:485505
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:399421
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:1352
    KRAB; KRAB box
    pfam13465
    Location:413438
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001145078.2NP_001138550.1  zinc finger protein 805 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 5' coding region, compared to variant 1. This difference causes translation initiation at a downstream AUG and results in an isoform (2) with a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AC005261, AK297977
    Consensus CDS
    CCDS46208.1
    UniProtKB/Swiss-Prot
    Q5CZA5
    Related
    ENSP00000365414.2, ENST00000354309.4
    Conserved Domains (3) summary
    COG5048
    Location:59435
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:352372
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:280305
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    57240632..57262728
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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