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ONECUT3 one cut homeobox 3 [ Homo sapiens (human) ]

Gene ID: 390874, updated on 18-Aug-2020

Summary

Official Symbol
ONECUT3provided by HGNC
Official Full Name
one cut homeobox 3provided by HGNC
Primary source
HGNC:HGNC:13399
See related
Ensembl:ENSG00000205922 MIM:611294
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OC3
Expression
Biased expression in stomach (RPKM 1.8) and duodenum (RPKM 0.1) See more
Orthologs

Genomic context

See ONECUT3 in Genome Data Viewer
Location:
19p13.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (1753506..1780988)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (1753662..1775444)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ubiquinol-cytochrome c reductase, complex III subunit XI Neighboring gene RNA, U6 small nuclear 1223, pseudogene Neighboring gene transcription factor 3 Neighboring gene uncharacterized LOC101928543 Neighboring gene ATPase phospholipid transporting 8B3 Neighboring gene microRNA 1909 Neighboring gene RNA exonuclease 1 homolog

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nuclear chromatin ISA
Inferred from Sequence Alignment
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription factor complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
one cut domain family member 3
Names
OC-3
transcription factor ONECUT-3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080488.2NP_001073957.1  one cut domain family member 3

    See identical proteins and their annotated locations for NP_001073957.1

    Status: VALIDATED

    Source sequence(s)
    AC004755, AC005256
    Consensus CDS
    CCDS45900.1
    UniProtKB/Swiss-Prot
    O60422
    Related
    ENSP00000371786.4, ENST00000382349.5
    Conserved Domains (2) summary
    smart00389
    Location:414469
    HOX; Homeodomain
    pfam02376
    Location:319391
    CUT; CUT domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    1753506..1780988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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