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GDPGP1 GDP-D-glucose phosphorylase 1 [ Homo sapiens (human) ]

Gene ID: 390637, updated on 6-Nov-2022

Summary

Official Symbol
GDPGP1provided by HGNC
Official Full Name
GDP-D-glucose phosphorylase 1provided by HGNC
Primary source
HGNC:HGNC:34360
See related
Ensembl:ENSG00000183208 MIM:619240; AllianceGenome:HGNC:34360
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
VTC2; C15orf58
Summary
Enables GDP-D-glucose phosphorylase activity. Involved in glucose metabolic process. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in duodenum (RPKM 1.5), testis (RPKM 1.4) and 25 other tissues See more
Orthologs
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Genomic context

See GDPGP1 in Genome Data Viewer
Location:
15q26.1
Exon count:
5
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (90234209..90245811)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (87990216..88001816)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (90777441..90789043)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 346, pseudogene Neighboring gene semaphorin 4B Neighboring gene ribosomal protein S12 pseudogene 26 Neighboring gene calcium and integrin binding 1 Neighboring gene tubulin tyrosine ligase like 13 Neighboring gene neugrin, neurite outgrowth associated

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables GDP-D-glucose phosphorylase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables GDP-D-glucose phosphorylase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in glucose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in glucose metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
GDP-D-glucose phosphorylase 1
Names
GDP-D-glucose phosphorylase C15orf58
NP_001013679.2
NP_001309740.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013657.3NP_001013679.2  GDP-D-glucose phosphorylase 1

    See identical proteins and their annotated locations for NP_001013679.2

    Status: VALIDATED

    Source sequence(s)
    AC091167, BX440248
    Consensus CDS
    CCDS32327.1
    UniProtKB/Swiss-Prot
    Q6ZNW5
    UniProtKB/TrEMBL
    A0A024RC68
    Related
    ENSP00000368405.3, ENST00000329600.8
    Conserved Domains (1) summary
    cl14728
    Location:26383
    DUF4922; Domain of unknown function (DUF4922)
  2. NM_001322811.2NP_001309740.1  GDP-D-glucose phosphorylase 1

    Status: VALIDATED

    Source sequence(s)
    AC091167
    Consensus CDS
    CCDS32327.1
    UniProtKB/Swiss-Prot
    Q6ZNW5
    UniProtKB/TrEMBL
    A0A024RC68
    Related
    ENSP00000453822.2, ENST00000559204.6
    Conserved Domains (1) summary
    cl14728
    Location:26383
    DUF4922; Domain of unknown function (DUF4922)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    90234209..90245811
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    87990216..88001816
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)