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OR11H4 olfactory receptor family 11 subfamily H member 4 [ Homo sapiens (human) ]

Gene ID: 390442, updated on 13-Mar-2020

Summary

Official Symbol
OR11H4provided by HGNC
Official Full Name
olfactory receptor family 11 subfamily H member 4provided by HGNC
Primary source
HGNC:HGNC:15347
See related
Ensembl:ENSG00000176198
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR14-36
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs

Genomic context

See OR11H4 in Genome Data Viewer
Location:
14q11.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (20242792..20243766)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (20710951..20711925)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 11 subfamily H member 6 Neighboring gene olfactory receptor family 11 subfamily H member 7 (gene/pseudogene) Neighboring gene tetratricopeptide repeat domain 5 Neighboring gene cyclin B1 interacting protein 1 Neighboring gene small nucleolar RNA, H/ACA box 79B

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled serotonin receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neurotransmitter receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
dendrite IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 
synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 11H4
Names
olfactory receptor OR14-36

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004479.1NP_001004479.1  olfactory receptor 11H4

    See identical proteins and their annotated locations for NP_001004479.1

    Status: PROVISIONAL

    Source sequence(s)
    AB065887
    Consensus CDS
    CCDS32034.1
    UniProtKB/Swiss-Prot
    Q8NGC9
    UniProtKB/TrEMBL
    A0A126GW19
    Related
    ENSP00000318997.2, ENST00000315409.2
    Conserved Domains (2) summary
    pfam00001
    Location:51300
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:41315
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    20242792..20243766
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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