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OR6X1 olfactory receptor family 6 subfamily X member 1 [ Homo sapiens (human) ]

Gene ID: 390260, updated on 11-Jun-2021

Summary

Official Symbol
OR6X1provided by HGNC
Official Full Name
olfactory receptor family 6 subfamily X member 1provided by HGNC
Primary source
HGNC:HGNC:14737
See related
Ensembl:ENSG00000221931
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-270
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR6X1 in Genome Data Viewer
Location:
11q24.1
Exon count:
1
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (123753580..123754518, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (123624288..123625226, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene sodium voltage-gated channel beta subunit 3 Neighboring gene uncharacterized LOC105369543 Neighboring gene zinc finger protein 202 Neighboring gene RNA, U1 small nuclear 21, pseudogene Neighboring gene uncharacterized LOC105369544 Neighboring gene olfactory receptor family 6 subfamily M member 1

Genomic regions, transcripts, and products

Phenotypes

Associated conditions

Description Tests
A genome-wide association study of total serum and mite-specific IgEs in asthma patients.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 6X1
Names
olfactory receptor OR11-270

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005188.1NP_001005188.1  olfactory receptor 6X1

    See identical proteins and their annotated locations for NP_001005188.1

    Status: VALIDATED

    Source sequence(s)
    AB065510
    Consensus CDS
    CCDS31695.1
    UniProtKB/Swiss-Prot
    Q8NH79
    UniProtKB/TrEMBL
    A0A126GVM0
    Related
    ENSP00000333724.2, ENST00000327930.3
    Conserved Domains (2) summary
    pfam00001
    Location:39288
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:31303
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    123753580..123754518 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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