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OR8H2 olfactory receptor family 8 subfamily H member 2 [ Homo sapiens (human) ]

Gene ID: 390151, updated on 26-Oct-2022

Summary

Official Symbol
OR8H2provided by HGNC
Official Full Name
olfactory receptor family 8 subfamily H member 2provided by HGNC
Primary source
HGNC:HGNC:15308
See related
Ensembl:ENSG00000181767 AllianceGenome:HGNC:15308
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-171
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR8H2 in Genome Data Viewer
Location:
11q12.1
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (56103687..56107658)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (56042036..56046005)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (55871163..55875134)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 8 subfamily I member 2 Neighboring gene olfactory receptor family 8 subfamily I member 4 pseudogene Neighboring gene olfactory receptor family 5 subfamily BN member 2 pseudogene Neighboring gene olfactory receptor family 8 subfamily H member 3

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
 
involved_in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 8H2
Names
olfactory receptor OR11-171

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005200.2NP_001005200.1  olfactory receptor 8H2

    See identical proteins and their annotated locations for NP_001005200.1

    Status: VALIDATED

    Source sequence(s)
    AC068339
    Consensus CDS
    CCDS31518.1
    UniProtKB/Swiss-Prot
    Q6IFC1, Q8N162
    Related
    ENSP00000493031.1, ENST00000641311.1
    Conserved Domains (1) summary
    cd15411
    Location:26303
    7tmA_OR8H-like; olfactory receptor subfamily 8H and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_001386064.1NP_001372993.1  olfactory receptor 8H2

    Status: VALIDATED

    Source sequence(s)
    AC068339
    Consensus CDS
    CCDS31518.1
    UniProtKB/Swiss-Prot
    Q6IFC1
    Related
    ENSP00000323982.1, ENST00000313503.2
    Conserved Domains (1) summary
    cd15411
    Location:26303
    7tmA_OR8H-like; olfactory receptor subfamily 8H and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    56103687..56107658
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    56042036..56046005
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)