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OR10A6 olfactory receptor family 10 subfamily A member 6 (gene/pseudogene) [ Homo sapiens (human) ]

Gene ID: 390093, updated on 22-Sep-2022

Summary

Official Symbol
OR10A6provided by HGNC
Official Full Name
olfactory receptor family 10 subfamily A member 6 (gene/pseudogene)provided by HGNC
Primary source
HGNC:HGNC:15132
See related
Ensembl:ENSG00000279000 AllianceGenome:HGNC:15132
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-96
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]
Annotation information
Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
Orthologs
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Genomic context

See OR10A6 in Genome Data Viewer
Location:
11p15.4
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (7924592..7931268, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (8003727..8010438, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (7946139..7952815, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC283299 Neighboring gene RNA, U6 small nuclear 943, pseudogene Neighboring gene uncharacterized LOC107984307 Neighboring gene olfactory receptor family 10 subfamily A member 3 Neighboring gene NLR family pyrin domain containing 10

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 10A6
Names
olfactory receptor OR11-96
olfactory receptor, family 10, subfamily A, member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004461.2NP_001004461.1  olfactory receptor 10A6 isoform 1

    See identical proteins and their annotated locations for NP_001004461.1

    Status: VALIDATED

    Source sequence(s)
    AC044810
    UniProtKB/Swiss-Prot
    Q6IF59, Q8NH74
    UniProtKB/TrEMBL
    A0A126GVN8
    Related
    ENSP00000493068.1, ENST00000641238.1
    Conserved Domains (1) summary
    cd15225
    Location:27301
    7tmA_OR10A-like; olfactory receptor subfamily 10A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_001389574.1NP_001376503.1  olfactory receptor 10A6 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC044810
    UniProtKB/Swiss-Prot
    Q6IF59
    UniProtKB/TrEMBL
    A0A126GVN8
    Related
    ENSP00000492919.1, ENST00000642108.1
    Conserved Domains (1) summary
    cd15225
    Location:27301
    7tmA_OR10A-like; olfactory receptor subfamily 10A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    7924592..7931268 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_011332695.1 Reference GRCh38.p14 PATCHES

    Range
    155586..162262 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187583.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    156093..162769 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    8003727..8010438 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)