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OR52A5 olfactory receptor family 52 subfamily A member 5 [ Homo sapiens (human) ]

Gene ID: 390054, updated on 22-Sep-2022

Summary

Official Symbol
OR52A5provided by HGNC
Official Full Name
olfactory receptor family 52 subfamily A member 5provided by HGNC
Primary source
HGNC:HGNC:19580
See related
Ensembl:ENSG00000171944 AllianceGenome:HGNC:19580
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-33
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR52A5 in Genome Data Viewer
Location:
11p15.4
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (5128776..5138356, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (5188115..5197698, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (5150006..5159586, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 52 subfamily J member 1 pseudogene Neighboring gene olfactory receptor family 52 subfamily A member 4 pseudogene Neighboring gene hereditary persistence of fetal hemoglobin-1 and -2 3' breakpoint enhancers Neighboring gene olfactory receptor family 52 subfamily A member 1 Neighboring gene hereditary persistence of fetal hemoglobin-6 3' breakpoint enhancer Neighboring gene olfactory receptor family 51 subfamily A member 1 pseudogene

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in membrane NAS
Non-traceable Author Statement
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 52A5
Names
odorant receptor HOR3'beta5
olfactory receptor OR11-33

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005160.3NP_001005160.1  olfactory receptor 52A5

    See identical proteins and their annotated locations for NP_001005160.1

    Status: VALIDATED

    Source sequence(s)
    AC129505
    Consensus CDS
    CCDS31373.1
    UniProtKB/Swiss-Prot
    Q9H2C5
    UniProtKB/TrEMBL
    A0A126GWD2
    Related
    ENSP00000303469.1, ENST00000307388.2
    Conserved Domains (2) summary
    pfam00001
    Location:43295
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:33313
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    5128776..5138356 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    5188115..5197698 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)