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C1QL3 complement C1q like 3 [ Homo sapiens (human) ]

Gene ID: 389941, updated on 22-Sep-2022

Summary

Official Symbol
C1QL3provided by HGNC
Official Full Name
complement C1q like 3provided by HGNC
Primary source
HGNC:HGNC:19359
See related
Ensembl:ENSG00000165985 MIM:615227; AllianceGenome:HGNC:19359
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C1ql; K100; CTRP13; C1QTNF13
Summary
Predicted to enable identical protein binding activity. Predicted to act upstream of or within regulation of synapse organization. Predicted to be located in extracellular region. Predicted to be part of collagen trimer. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in brain (RPKM 20.3), kidney (RPKM 2.3) and 3 other tissues See more
Orthologs
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Genomic context

See C1QL3 in Genome Data Viewer
Location:
10p13
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (16513734..16521879, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (16532178..16540346, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (16555733..16563878, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene phosphotriesterase related Neighboring gene RNA, U2 small nuclear 18, pseudogene Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:16639108-16640307 Neighboring gene Ras suppressor protein 1 Neighboring gene uncharacterized LOC124902385

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in neurotransmitter receptor localization to postsynaptic specialization membrane IEA
Inferred from Electronic Annotation
more info
 
involved_in postsynaptic density assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of synapse organization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of collagen trimer IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 
located_in hippocampal mossy fiber to CA3 synapse IEA
Inferred from Electronic Annotation
more info
 
located_in synaptic cleft IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
complement C1q-like protein 3
Names
C1q and tumor necrosis factor-related protein 13
C1q/TNF-related protein 13
complement component 1, q subcomponent-like 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001010908.2NP_001010908.1  complement C1q-like protein 3 precursor

    See identical proteins and their annotated locations for NP_001010908.1

    Status: VALIDATED

    Source sequence(s)
    AL353576, AL360230
    Consensus CDS
    CCDS31156.1
    UniProtKB/Swiss-Prot
    A0PJY5, Q5VWW1
    UniProtKB/TrEMBL
    A0A3B0J0F3
    Related
    ENSP00000298943.3, ENST00000298943.4
    Conserved Domains (1) summary
    pfam00386
    Location:128252
    C1q; C1q domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    16513734..16521879 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    16532178..16540346 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)