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XRCC6P2 X-ray repair cross complementing 6 pseudogene 2 [ Homo sapiens (human) ]

Gene ID: 389901, updated on 17-Sep-2024

Summary

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Official Symbol
XRCC6P2provided by HGNC
Official Full Name
X-ray repair cross complementing 6 pseudogene 2provided by HGNC
Primary source
HGNC:HGNC:45184
See related
Ensembl:ENSG00000234825 AllianceGenome:HGNC:45184
Gene type
pseudo
RefSeq status
MODEL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
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Genomic context

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See XRCC6P2 in Genome Data Viewer
Location:
Xq28
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (150230839..150232825, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (148498400..148500384, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:149289377-149289876 Neighboring gene nucleolar protein 11 pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:149385283-149385784 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:149385785-149386284 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chrX:149387913-149388449 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chrX:149393501-149394088 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chrX:149394089-149394674 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:149406763-149407264 Neighboring gene microRNA 2114 Neighboring gene mastermind like domain containing 1 Neighboring gene uncharacterized LOC124905223 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:149733744-149734666 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:149734667-149735588 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21050 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 30021 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 30022 Neighboring gene myotubularin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors. Subramanian C, et al. Proc Natl Acad Sci U S A, 2005 Mar 29. PMID 15778293, Free PMC Article
  2. Ku is a novel transcriptional recycling coactivator of the androgen receptor in prostate cancer cells. Mayeur GL, et al. J Biol Chem, 2005 Mar 18. PMID 15640154

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Ku is involved in transcriptional recycling with androgen dependent promoters
    Title: Ku is a novel transcriptional recycling coactivator of the androgen receptor in prostate cancer cells.
  2. Ku70 binds Bax in an acetylation-sensitive manner, thus blocking apoptosis, and is a molecular target for the antineoplastic actions of Histone deacetylase inhibitors.
    Title: Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh38)

General gene information

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Markers

Other Names

  • X-ray repair complementing defective repair in Chinese hamster cells 6 pseudogene 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    150230839..150232825 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    148498400..148500384 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Research Materials