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rhea [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38978, updated on 26-Aug-2021

Summary

Official Symbol
rheaprovided by FlyBase
Primary source
FLYBASE:FBgn0260442
Locus tag
Dmel_CG6831
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6831; CT21159; Dmel\CG6831; Rhea; talin; Talin; tendrils; Tln
Old locus tag
CG6831
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Genomic context

See rhea in Genome Data Viewer
Location:
66D6-66D7; 3-26 cM
Exon count:
22
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (8545001..8574409)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (8538101..8567509)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene fear-of-intimacy Neighboring gene ergic53 Neighboring gene long non-coding RNA:CR43910 Neighboring gene mir-190 stem loop Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Negative elongation factor E Neighboring gene Ribosomal protein L14

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 
enables integrin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables integrin binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Z disc HDA PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
is_active_in focal adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in focal adhesion IDA
Inferred from Direct Assay
more info
PubMed 
located_in focal adhesion ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in plasma membrane HDA PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in ruffle IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
rhea
Names
CG6831-PB
CG6831-PC
CG6831-PD
CG6831-PE
CG6831-PF
CG6831-PG
CG6831-PH
CG6831-PI
rhea-PB
rhea-PC
rhea-PD
rhea-PE
rhea-PF
rhea-PG
rhea-PH
rhea-PI
talin
tendrils

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    8545001..8574409
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259745.2NP_001246674.1  rhea, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246674.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VSL8
    Related
    FBpp0293740, FBtr0305210
    Conserved Domains (12) summary
    cd12150
    Location:16611832
    talin-RS; rod-segment of the talin C-terminal domain
    smart00295
    Location:89322
    B41; Band 4.1 homologues
    COG0840
    Location:16942005
    Tar; Methyl-accepting chemotaxis protein [Cell motility, Signal transduction mechanisms]
    cd10569
    Location:318409
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam00373
    Location:215322
    FERM_M; FERM central domain
    pfam01044
    Location:8741035
    Vinculin; Vinculin family
    pfam01608
    Location:23922534
    I_LWEQ; I/LWEQ domain
    pfam08913
    Location:18591982
    VBS; Vinculin Binding Site
    pfam09141
    Location:510668
    Talin_middle; Talin, middle domain
    pfam09379
    Location:92147
    FERM_N; FERM N-terminal domain
    pfam16511
    Location:485
    FERM_f0; N-terminal or F0 domain of Talin-head FERM
    cl19756
    Location:686778
    I_LWEQ; I/LWEQ domain
  2. NM_001274658.1NP_001261587.1  rhea, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261587.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PBW9
    Related
    FBpp0305319, FBtr0333107
    Conserved Domains (12) summary
    cd12150
    Location:16401811
    talin-RS; rod-segment of the talin C-terminal domain
    smart00295
    Location:89322
    B41; Band 4.1 homologues
    COG0840
    Location:16731984
    Tar; Methyl-accepting chemotaxis protein [Cell motility, Signal transduction mechanisms]
    cd10569
    Location:318409
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam00373
    Location:215322
    FERM_M; FERM central domain
    pfam01044
    Location:8531014
    Vinculin; Vinculin family
    pfam01608
    Location:23712513
    I_LWEQ; I/LWEQ domain
    pfam08913
    Location:18381961
    VBS; Vinculin Binding Site
    pfam09141
    Location:489647
    Talin_middle; Talin, middle domain
    pfam09379
    Location:92147
    FERM_N; FERM N-terminal domain
    pfam16511
    Location:485
    FERM_f0; N-terminal or F0 domain of Talin-head FERM
    cl19756
    Location:665757
    I_LWEQ; I/LWEQ domain
  3. NM_001259746.2NP_001246675.1  rhea, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246675.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NDM3
    Related
    FBpp0293741, FBtr0305211
    Conserved Domains (11) summary
    cd12150
    Location:16611832
    talin-RS; rod-segment of the talin C-terminal domain
    smart00295
    Location:89322
    B41; Band 4.1 homologues
    COG0840
    Location:16942005
    Tar; Methyl-accepting chemotaxis protein [Cell motility, Signal transduction mechanisms]
    cd10569
    Location:318409
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam00373
    Location:215322
    FERM_M; FERM central domain
    pfam01044
    Location:8741035
    Vinculin; Vinculin family
    pfam08913
    Location:18591982
    VBS; Vinculin Binding Site
    pfam09141
    Location:510668
    Talin_middle; Talin, middle domain
    pfam09379
    Location:92147
    FERM_N; FERM N-terminal domain
    pfam16511
    Location:485
    FERM_f0; N-terminal or F0 domain of Talin-head FERM
    cl19756
    Location:686778
    I_LWEQ; I/LWEQ domain
  4. NM_001274659.1NP_001261588.1  rhea, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261588.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PEJ8
    Related
    FBpp0305320, FBtr0333108
    Conserved Domains (12) summary
    cd12150
    Location:16611832
    talin-RS; rod-segment of the talin C-terminal domain
    smart00295
    Location:89322
    B41; Band 4.1 homologues
    COG0840
    Location:16942005
    Tar; Methyl-accepting chemotaxis protein [Cell motility, Signal transduction mechanisms]
    cd10569
    Location:318409
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam00373
    Location:215322
    FERM_M; FERM central domain
    pfam01044
    Location:8741035
    Vinculin; Vinculin family
    pfam01608
    Location:23922534
    I_LWEQ; I/LWEQ domain
    pfam08913
    Location:18591982
    VBS; Vinculin Binding Site
    pfam09141
    Location:510668
    Talin_middle; Talin, middle domain
    pfam09379
    Location:92147
    FERM_N; FERM N-terminal domain
    pfam16511
    Location:485
    FERM_f0; N-terminal or F0 domain of Talin-head FERM
    cl19756
    Location:686778
    I_LWEQ; I/LWEQ domain
  5. NM_001274660.1NP_001261589.1  rhea, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261589.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PF06
    Related
    FBpp0305321, FBtr0333109
    Conserved Domains (5) summary
    smart00295
    Location:89322
    B41; Band 4.1 homologues
    cd10569
    Location:318409
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam00373
    Location:215322
    FERM_M; FERM central domain
    pfam09379
    Location:92147
    FERM_N; FERM N-terminal domain
    pfam16511
    Location:485
    FERM_f0; N-terminal or F0 domain of Talin-head FERM
  6. NM_001259747.2NP_001246676.1  rhea, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246676.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NDM3
    Related
    FBpp0293742, FBtr0305212
    Conserved Domains (11) summary
    cd12150
    Location:16611832
    talin-RS; rod-segment of the talin C-terminal domain
    smart00295
    Location:89322
    B41; Band 4.1 homologues
    COG0840
    Location:16942005
    Tar; Methyl-accepting chemotaxis protein [Cell motility, Signal transduction mechanisms]
    cd10569
    Location:318409
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam00373
    Location:215322
    FERM_M; FERM central domain
    pfam01044
    Location:8741035
    Vinculin; Vinculin family
    pfam08913
    Location:18591982
    VBS; Vinculin Binding Site
    pfam09141
    Location:510668
    Talin_middle; Talin, middle domain
    pfam09379
    Location:92147
    FERM_N; FERM N-terminal domain
    pfam16511
    Location:485
    FERM_f0; N-terminal or F0 domain of Talin-head FERM
    cl19756
    Location:686778
    I_LWEQ; I/LWEQ domain
  7. NM_001274657.1NP_001261586.1  rhea, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261586.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VSL8
    Related
    FBpp0305317, FBtr0333105
    Conserved Domains (12) summary
    cd12150
    Location:16611832
    talin-RS; rod-segment of the talin C-terminal domain
    smart00295
    Location:89322
    B41; Band 4.1 homologues
    COG0840
    Location:16942005
    Tar; Methyl-accepting chemotaxis protein [Cell motility, Signal transduction mechanisms]
    cd10569
    Location:318409
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam00373
    Location:215322
    FERM_M; FERM central domain
    pfam01044
    Location:8741035
    Vinculin; Vinculin family
    pfam01608
    Location:23922534
    I_LWEQ; I/LWEQ domain
    pfam08913
    Location:18591982
    VBS; Vinculin Binding Site
    pfam09141
    Location:510668
    Talin_middle; Talin, middle domain
    pfam09379
    Location:92147
    FERM_N; FERM N-terminal domain
    pfam16511
    Location:485
    FERM_f0; N-terminal or F0 domain of Talin-head FERM
    cl19756
    Location:686778
    I_LWEQ; I/LWEQ domain
  8. NM_139981.4NP_648238.1  rhea, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648238.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VSL8
    Related
    FBpp0305318, FBtr0333106
    Conserved Domains (12) summary
    cd12150
    Location:16611832
    talin-RS; rod-segment of the talin C-terminal domain
    smart00295
    Location:89322
    B41; Band 4.1 homologues
    COG0840
    Location:16942005
    Tar; Methyl-accepting chemotaxis protein [Cell motility, Signal transduction mechanisms]
    cd10569
    Location:318409
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam00373
    Location:215322
    FERM_M; FERM central domain
    pfam01044
    Location:8741035
    Vinculin; Vinculin family
    pfam01608
    Location:23922534
    I_LWEQ; I/LWEQ domain
    pfam08913
    Location:18591982
    VBS; Vinculin Binding Site
    pfam09141
    Location:510668
    Talin_middle; Talin, middle domain
    pfam09379
    Location:92147
    FERM_N; FERM N-terminal domain
    pfam16511
    Location:485
    FERM_f0; N-terminal or F0 domain of Talin-head FERM
    cl19756
    Location:686778
    I_LWEQ; I/LWEQ domain
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