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GLIDR glioblastoma down-regulated RNA [ Homo sapiens (human) ]

Gene ID: 389741, updated on 10-Dec-2024

Summary

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Official Symbol
GLIDRprovided by HGNC
Official Full Name
glioblastoma down-regulated RNAprovided by HGNC
Primary source
HGNC:HGNC:48823
See related
Ensembl:ENSG00000278175 AllianceGenome:HGNC:48823
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM88A; LINC01172; TCONS_00015562
Expression
Ubiquitous expression in thyroid (RPKM 3.8), brain (RPKM 3.6) and 25 other tissues See more
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Genomic context

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See GLIDR in Genome Data Viewer
Location:
9p12
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (39803496..39810159, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (39817620..39824283, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (41948514..41955177, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene RBPJ pseudogene 5 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:41926459-41927010 Neighboring gene CNTNAP3 pseudogene 6 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:41936783-41937617 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:41942506-41943030 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:41943031-41943555 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28420 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28421 Neighboring gene fibroblast growth factor 7 pseudogene 3 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr9:41997761-41998747 Neighboring gene family with sequence similarity 88 member D Neighboring gene RNA, 7SL, cytoplasmic 763, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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Related articles in PubMed

  1. Increased expression of long non-coding RNA GLIDR in prostate cancer. Zhang Y, et al. Cancer Biomark, 2017. PMID 28211799
  2. GLIDR promotes the aggressiveness progression of prostate cancer cells by sponging miR-128-3p. Li S, et al. Pathol Res Pract, 2023 Feb. PMID 36709726
  3. Long non-coding RNA GLIDR accelerates the tumorigenesis of lung adenocarcinoma by miR-1270/TCF12 axis. Tai G, et al. Cell Cycle, 2021 Sep. PMID 34369267, Free PMC Article
  4. A long non-coding RNA signature in glioblastoma multiforme predicts survival. Zhang XQ, et al. Neurobiol Dis, 2013 Oct. PMID 23726844
  5. Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism. Antoniali G, et al. Nat Commun, 2017 Oct 6. PMID 28986522, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. GLIDR promotes the aggressiveness progression of prostate cancer cells by sponging miR-128-3p.
    Title: GLIDR promotes the aggressiveness progression of prostate cancer cells by sponging miR-128-3p.
  2. Long non-coding RNA GLIDR accelerates the tumorigenesis of lung adenocarcinoma by miR-1270/TCF12 axis.
    Title: Long non-coding RNA GLIDR accelerates the tumorigenesis of lung adenocarcinoma by miR-1270/TCF12 axis.
  3. Increased GLIDR expression is associated with prostate cancer.
    Title: Increased expression of long non-coding RNA GLIDR in prostate cancer.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Other Names

  • Putative UPF0633 protein MGC21881
  • family with sequence similarity 88 member A
  • long intergenic non-protein coding RNA 1172

Clone Names

  • MGC21881

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_015363.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript.
    Source sequence(s)
    BX664615
    Related
    ENST00000618092.4

  2. NR_126044.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 3' exon, and terminates early and is shorter than variant 1.
    Source sequence(s)
    BX664615
    Related
    ENST00000625350.1

  3. NR_126045.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice site and lacks an internal segment, and terminates early and is shorter than variant 1.
    Source sequence(s)
    BX664615
    Related
    ENST00000839125.1

  4. NR_126046.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs at both the 5' and 3' ends, and is shorter than variant 1.
    Source sequence(s)
    BC019880, BX664615
    Related
    ENST00000666906.4

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    39803496..39810159 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    39817620..39824283 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_203448.1: Suppressed sequence

    Description
    NM_203448.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
Nucleotide Protein
Heading Accession and Version

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