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RBM12B RNA binding motif protein 12B [ Homo sapiens (human) ]

Gene ID: 389677, updated on 23-Nov-2021

Summary

Official Symbol
RBM12Bprovided by HGNC
Official Full Name
RNA binding motif protein 12Bprovided by HGNC
Primary source
HGNC:HGNC:32310
See related
Ensembl:ENSG00000183808
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MGC:33837
Expression
Ubiquitous expression in testis (RPKM 5.9), ovary (RPKM 4.2) and 25 other tissues See more
Orthologs
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Genomic context

See RBM12B in Genome Data Viewer
Location:
8q22.1
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (93728155..93741012, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (94740383..94753237, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene CIBAR1 divergent transcript Neighboring gene uncharacterized LOC105375641 Neighboring gene zinc finger protein 317 pseudogene 1 Neighboring gene CBY1 interacting BAR domain containing 1 Neighboring gene RBM12B antisense RNA 1 Neighboring gene RBM12B divergent transcript Neighboring gene transmembrane protein 67

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of RNA splicing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001377960.1NP_001364889.1  RNA-binding protein 12B

    Status: VALIDATED

    Source sequence(s)
    AC010834
    Related
    ENSP00000429807.2, ENST00000520560.6
    Conserved Domains (7) summary
    PTZ00121
    Location:449680
    PTZ00121; MAEBL; Provisional
    PHA03321
    Location:689915
    PHA03321; tegument protein VP11/12; Provisional
    cd12513
    Location:284363
    RRM3_RBM12B; RNA recognition motif 3 (RRM3) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12744
    Location:280
    RRM1_RBM12B; RNA recognition motif 1 (RRM1) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12746
    Location:153238
    RRM2_RBM12B; RNA recognition motif 2 (RRM2) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12748
    Location:400475
    RRM4_RBM12B; RNA recognition motif 4 (RRM4) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12750
    Location:9251001
    RRM5_RBM12B; RNA recognition motif 5 (RRM5) found in RNA-binding protein 12B (RBM12B) and similar proteins
  2. NM_001377961.1NP_001364890.1  RNA-binding protein 12B

    Status: VALIDATED

    Source sequence(s)
    AC010834
    Conserved Domains (7) summary
    PTZ00121
    Location:449680
    PTZ00121; MAEBL; Provisional
    PHA03321
    Location:689915
    PHA03321; tegument protein VP11/12; Provisional
    cd12513
    Location:284363
    RRM3_RBM12B; RNA recognition motif 3 (RRM3) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12744
    Location:280
    RRM1_RBM12B; RNA recognition motif 1 (RRM1) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12746
    Location:153238
    RRM2_RBM12B; RNA recognition motif 2 (RRM2) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12748
    Location:400475
    RRM4_RBM12B; RNA recognition motif 4 (RRM4) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12750
    Location:9251001
    RRM5_RBM12B; RNA recognition motif 5 (RRM5) found in RNA-binding protein 12B (RBM12B) and similar proteins
  3. NM_001377962.1NP_001364891.1  RNA-binding protein 12B

    Status: VALIDATED

    Source sequence(s)
    AC010834
    Conserved Domains (7) summary
    PTZ00121
    Location:449680
    PTZ00121; MAEBL; Provisional
    PHA03321
    Location:689915
    PHA03321; tegument protein VP11/12; Provisional
    cd12513
    Location:284363
    RRM3_RBM12B; RNA recognition motif 3 (RRM3) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12744
    Location:280
    RRM1_RBM12B; RNA recognition motif 1 (RRM1) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12746
    Location:153238
    RRM2_RBM12B; RNA recognition motif 2 (RRM2) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12748
    Location:400475
    RRM4_RBM12B; RNA recognition motif 4 (RRM4) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12750
    Location:9251001
    RRM5_RBM12B; RNA recognition motif 5 (RRM5) found in RNA-binding protein 12B (RBM12B) and similar proteins
  4. NM_001377963.1NP_001364892.1  RNA-binding protein 12B

    Status: VALIDATED

    Source sequence(s)
    AC010834
    Related
    ENSP00000430474.2, ENST00000519109.6
    Conserved Domains (7) summary
    PTZ00121
    Location:449680
    PTZ00121; MAEBL; Provisional
    PHA03321
    Location:689915
    PHA03321; tegument protein VP11/12; Provisional
    cd12513
    Location:284363
    RRM3_RBM12B; RNA recognition motif 3 (RRM3) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12744
    Location:280
    RRM1_RBM12B; RNA recognition motif 1 (RRM1) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12746
    Location:153238
    RRM2_RBM12B; RNA recognition motif 2 (RRM2) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12748
    Location:400475
    RRM4_RBM12B; RNA recognition motif 4 (RRM4) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12750
    Location:9251001
    RRM5_RBM12B; RNA recognition motif 5 (RRM5) found in RNA-binding protein 12B (RBM12B) and similar proteins
  5. NM_001377964.1NP_001364893.1  RNA-binding protein 12B

    Status: VALIDATED

    Source sequence(s)
    AC010834
    Conserved Domains (7) summary
    PTZ00121
    Location:449680
    PTZ00121; MAEBL; Provisional
    PHA03321
    Location:689915
    PHA03321; tegument protein VP11/12; Provisional
    cd12513
    Location:284363
    RRM3_RBM12B; RNA recognition motif 3 (RRM3) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12744
    Location:280
    RRM1_RBM12B; RNA recognition motif 1 (RRM1) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12746
    Location:153238
    RRM2_RBM12B; RNA recognition motif 2 (RRM2) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12748
    Location:400475
    RRM4_RBM12B; RNA recognition motif 4 (RRM4) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12750
    Location:9251001
    RRM5_RBM12B; RNA recognition motif 5 (RRM5) found in RNA-binding protein 12B (RBM12B) and similar proteins
  6. NM_203390.4NP_976324.2  RNA-binding protein 12B

    See identical proteins and their annotated locations for NP_976324.2

    Status: VALIDATED

    Source sequence(s)
    AC010834, BC039260
    Consensus CDS
    CCDS43755.1
    UniProtKB/Swiss-Prot
    Q8IXT5
    Related
    ENSP00000382239.2, ENST00000399300.7
    Conserved Domains (7) summary
    PTZ00121
    Location:449680
    PTZ00121; MAEBL; Provisional
    PHA03321
    Location:689915
    PHA03321; tegument protein VP11/12; Provisional
    cd12513
    Location:284363
    RRM3_RBM12B; RNA recognition motif 3 (RRM3) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12744
    Location:280
    RRM1_RBM12B; RNA recognition motif 1 (RRM1) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12746
    Location:153238
    RRM2_RBM12B; RNA recognition motif 2 (RRM2) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12748
    Location:400475
    RRM4_RBM12B; RNA recognition motif 4 (RRM4) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12750
    Location:9251001
    RRM5_RBM12B; RNA recognition motif 5 (RRM5) found in RNA-binding protein 12B (RBM12B) and similar proteins

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    93728155..93741012 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011517029.2XP_011515331.1  RNA-binding protein 12B isoform X1

    See identical proteins and their annotated locations for XP_011515331.1

    UniProtKB/Swiss-Prot
    Q8IXT5
    Related
    ENSP00000428269.2, ENST00000518597.2
    Conserved Domains (7) summary
    PTZ00121
    Location:449680
    PTZ00121; MAEBL; Provisional
    PHA03321
    Location:689915
    PHA03321; tegument protein VP11/12; Provisional
    cd12513
    Location:284363
    RRM3_RBM12B; RNA recognition motif 3 (RRM3) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12744
    Location:280
    RRM1_RBM12B; RNA recognition motif 1 (RRM1) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12746
    Location:153238
    RRM2_RBM12B; RNA recognition motif 2 (RRM2) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12748
    Location:400475
    RRM4_RBM12B; RNA recognition motif 4 (RRM4) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12750
    Location:9251001
    RRM5_RBM12B; RNA recognition motif 5 (RRM5) found in RNA-binding protein 12B (RBM12B) and similar proteins
  2. XM_017013408.2XP_016868897.1  RNA-binding protein 12B isoform X1

    UniProtKB/Swiss-Prot
    Q8IXT5
    Related
    ENSP00000427729.2, ENST00000517700.6
    Conserved Domains (7) summary
    PTZ00121
    Location:449680
    PTZ00121; MAEBL; Provisional
    PHA03321
    Location:689915
    PHA03321; tegument protein VP11/12; Provisional
    cd12513
    Location:284363
    RRM3_RBM12B; RNA recognition motif 3 (RRM3) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12744
    Location:280
    RRM1_RBM12B; RNA recognition motif 1 (RRM1) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12746
    Location:153238
    RRM2_RBM12B; RNA recognition motif 2 (RRM2) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12748
    Location:400475
    RRM4_RBM12B; RNA recognition motif 4 (RRM4) found in RNA-binding protein 12B (RBM12B) and similar proteins
    cd12750
    Location:9251001
    RRM5_RBM12B; RNA recognition motif 5 (RRM5) found in RNA-binding protein 12B (RBM12B) and similar proteins
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