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BEND4 BEN domain containing 4 [ Homo sapiens (human) ]

Gene ID: 389206, updated on 12-Oct-2019

Summary

Official Symbol
BEND4provided by HGNC
Official Full Name
BEN domain containing 4provided by HGNC
Primary source
HGNC:HGNC:23815
See related
Ensembl:ENSG00000188848
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CCDC4
Expression
Biased expression in testis (RPKM 7.9), prostate (RPKM 2.2) and 4 other tissues See more
Orthologs

Genomic context

See BEND4 in Genome Data Viewer
Location:
4p13
Exon count:
6
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (42110853..42152655, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (42112870..42154895, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene DDB1 and CUL4 associated factor 4 like 1 Neighboring gene solute carrier family 30 member 9 Neighboring gene ATPase Na+/K+ transporting subunit beta 1 pseudogene 1 Neighboring gene VISTA enhancer hs847 Neighboring gene uncharacterized LOC105374428 Neighboring gene Sharpr-MPRA regulatory region 13490 Neighboring gene Sharpr-MPRA regulatory region 6384

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ35632, FLJ43965, MGC157807, MGC157808

General protein information

Preferred Names
BEN domain-containing protein 4
Names
coiled-coil domain containing 4
coiled-coil domain-containing protein 4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159547.2NP_001153019.1  BEN domain-containing protein 4 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1, that results in a frameshift. It encodes isoform b which has a shorter and distinct C-terminus compared to isoform a.
    Source sequence(s)
    AA757195, AB126829
    UniProtKB/Swiss-Prot
    Q6ZU67
    Related
    ENSP00000421160.1, ENST00000504360.5
    Conserved Domains (1) summary
    cl21462
    Location:325362
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
  2. NM_207406.4NP_997289.2  BEN domain-containing protein 4 isoform a

    See identical proteins and their annotated locations for NP_997289.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AA757195, AB126828
    Consensus CDS
    CCDS47048.1
    UniProtKB/Swiss-Prot
    Q6ZU67
    Related
    ENSP00000421169.1, ENST00000502486.6
    Conserved Domains (2) summary
    pfam10523
    Location:414489
    BEN; BEN domain
    cl21462
    Location:325362
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    42110853..42152655 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017008185.1XP_016863674.1  BEN domain-containing protein 4 isoform X1

    UniProtKB/Swiss-Prot
    Q6ZU67
    Conserved Domains (2) summary
    pfam10523
    Location:414489
    BEN; BEN domain
    cl21462
    Location:325362
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
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